Recombinant Mouse Kinesin-associated protein 3(Kifap3)

Product Type Recombinant Protein
Uniprot No. P70188
Species Mus musculus (Mouse)
Gene Names Kifap3
Protein Names Recommended name: Kinesin-associated protein 3 Short name= KAP-3 Short name= KAP3
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Target Details The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras; one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. This protein contains 9 Armadillo repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein.
HGNC 17060
RGD 1305191
MGI 107566
Function Involved in tethering the chromosomes to the spindle pole and in chromosome movement. Binds to the tail domain of the KIF3A/KIF3B heterodimer to form a heterotrimeric KIF3 complex and may regulate the membrane binding of this complex.
Database Links

KEGG: mmu:16579

STRING: 10090.ENSMUSP00000076830

UniGene: Mm.4651

Product Details for Different Expression Systems

Product Name Recombinant Mouse Kinesin-associated protein 3(Kifap3),Yeast
Code CSB-YP012347MO
Size Pls inquiry other sizes
Source Yeast
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MQGEDARYLK RKVKGGNIDV HPSEKALIVQ YEVEATILGE MGDPMLGERK ECQKIIRLKS LNANTDITSL ARKVVEECKL IHPSKLSEVE QLLYYLQNRR DSLPGKEKKE KSSKPKDPPP FEGMEIDEVA NINDMDEYIE LLYEDIPDKV RGSALILQLA RNPDNLEELL LNETALGALA RVLREDWKQS VELATNIIYI FFCFSSFSHF HGLITHYKIG ALCMNIIDHE LKRHELWQEE LSKKKKAVDE DLENQTLRKD YDKTFKKYQG LVVKQEQLLR VALYLLLNLA EDTRTELKMR NKNIVHMLVK ALDRDNFELL ILVVSFLKKL SIFMENKNDM VEMDIVEKLV KMIPCEHEDL LNITLRLLLN LSFDTGLRNK MVQVGLLPKL TALLGNENYK QIAMCVLYHI SMDDRFKSMF AYTDCIPQLM KMLFECSDER IDLELISFCI NLAANKRNVQ LICEGNGLKM LMKRALKLKD PLLMKMIRNI SQHDGPTKNL FIDYVGDLAA QISSDEEEEF VIECLGTLAN LTIPDLDWEL VLKEYKLVPF LKDKLKPGAA EDDLVLEVVI MIGTVSMDDS CAALLAKSGI IPALIELLNA QQEDDEFVCQ IIYVFYQMVF HQATRDVIIK ETQAPAYLID LMHDKNNEIR KVCDNTLDII AEYDEEWAKK IQSEKFRWHN SQWLEMVESR QLDESEQYLY GDDRIEPYIH EGDILERPDL FYNSDGLITS EGAISPDFFN DFHLQNGDVV GQHAFPGSLG MDGFGQPLGI LGRPATAYGF RPDEPYYYSF GSR
Expression Region 1-793
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
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Product Name Recombinant Mouse Kinesin-associated protein 3(Kifap3),E.coli
Code CSB-EP012347MO
Size Pls inquiry other sizes
Source E.coli
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-SUMO-tagged and C-terminal Myc-tagged
N-terminal His-B2M-tagged and C-terminal Myc-tagged
N-terminal His-GST-tagged and C-terminal Myc-tagged
N-terminal His-tagged
N-terminal His-SUMO-tagged
N-terminal His-B2M-tagged
N-terminal His-GST-tagged
N-terminal GST-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MQGEDARYLK RKVKGGNIDV HPSEKALIVQ YEVEATILGE MGDPMLGERK ECQKIIRLKS LNANTDITSL ARKVVEECKL IHPSKLSEVE QLLYYLQNRR DSLPGKEKKE KSSKPKDPPP FEGMEIDEVA NINDMDEYIE LLYEDIPDKV RGSALILQLA RNPDNLEELL LNETALGALA RVLREDWKQS VELATNIIYI FFCFSSFSHF HGLITHYKIG ALCMNIIDHE LKRHELWQEE LSKKKKAVDE DLENQTLRKD YDKTFKKYQG LVVKQEQLLR VALYLLLNLA EDTRTELKMR NKNIVHMLVK ALDRDNFELL ILVVSFLKKL SIFMENKNDM VEMDIVEKLV KMIPCEHEDL LNITLRLLLN LSFDTGLRNK MVQVGLLPKL TALLGNENYK QIAMCVLYHI SMDDRFKSMF AYTDCIPQLM KMLFECSDER IDLELISFCI NLAANKRNVQ LICEGNGLKM LMKRALKLKD PLLMKMIRNI SQHDGPTKNL FIDYVGDLAA QISSDEEEEF VIECLGTLAN LTIPDLDWEL VLKEYKLVPF LKDKLKPGAA EDDLVLEVVI MIGTVSMDDS CAALLAKSGI IPALIELLNA QQEDDEFVCQ IIYVFYQMVF HQATRDVIIK ETQAPAYLID LMHDKNNEIR KVCDNTLDII AEYDEEWAKK IQSEKFRWHN SQWLEMVESR QLDESEQYLY GDDRIEPYIH EGDILERPDL FYNSDGLITS EGAISPDFFN DFHLQNGDVV GQHAFPGSLG MDGFGQPLGI LGRPATAYGF RPDEPYYYSF GSR
Expression Region 1-793
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
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Product Name Recombinant Mouse Kinesin-associated protein 3(Kifap3),Baculovirus
Code CSB-BP012347MO
Size Pls inquiry other sizes
Source Baculovirus
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MQGEDARYLK RKVKGGNIDV HPSEKALIVQ YEVEATILGE MGDPMLGERK ECQKIIRLKS LNANTDITSL ARKVVEECKL IHPSKLSEVE QLLYYLQNRR DSLPGKEKKE KSSKPKDPPP FEGMEIDEVA NINDMDEYIE LLYEDIPDKV RGSALILQLA RNPDNLEELL LNETALGALA RVLREDWKQS VELATNIIYI FFCFSSFSHF HGLITHYKIG ALCMNIIDHE LKRHELWQEE LSKKKKAVDE DLENQTLRKD YDKTFKKYQG LVVKQEQLLR VALYLLLNLA EDTRTELKMR NKNIVHMLVK ALDRDNFELL ILVVSFLKKL SIFMENKNDM VEMDIVEKLV KMIPCEHEDL LNITLRLLLN LSFDTGLRNK MVQVGLLPKL TALLGNENYK QIAMCVLYHI SMDDRFKSMF AYTDCIPQLM KMLFECSDER IDLELISFCI NLAANKRNVQ LICEGNGLKM LMKRALKLKD PLLMKMIRNI SQHDGPTKNL FIDYVGDLAA QISSDEEEEF VIECLGTLAN LTIPDLDWEL VLKEYKLVPF LKDKLKPGAA EDDLVLEVVI MIGTVSMDDS CAALLAKSGI IPALIELLNA QQEDDEFVCQ IIYVFYQMVF HQATRDVIIK ETQAPAYLID LMHDKNNEIR KVCDNTLDII AEYDEEWAKK IQSEKFRWHN SQWLEMVESR QLDESEQYLY GDDRIEPYIH EGDILERPDL FYNSDGLITS EGAISPDFFN DFHLQNGDVV GQHAFPGSLG MDGFGQPLGI LGRPATAYGF RPDEPYYYSF GSR
Expression Region 1-793
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Mouse Kinesin-associated protein 3(Kifap3),Mammalian cell
Code CSB-MP012347MO
Size Pls inquiry other sizes
Source Mammalian cell
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MQGEDARYLK RKVKGGNIDV HPSEKALIVQ YEVEATILGE MGDPMLGERK ECQKIIRLKS LNANTDITSL ARKVVEECKL IHPSKLSEVE QLLYYLQNRR DSLPGKEKKE KSSKPKDPPP FEGMEIDEVA NINDMDEYIE LLYEDIPDKV RGSALILQLA RNPDNLEELL LNETALGALA RVLREDWKQS VELATNIIYI FFCFSSFSHF HGLITHYKIG ALCMNIIDHE LKRHELWQEE LSKKKKAVDE DLENQTLRKD YDKTFKKYQG LVVKQEQLLR VALYLLLNLA EDTRTELKMR NKNIVHMLVK ALDRDNFELL ILVVSFLKKL SIFMENKNDM VEMDIVEKLV KMIPCEHEDL LNITLRLLLN LSFDTGLRNK MVQVGLLPKL TALLGNENYK QIAMCVLYHI SMDDRFKSMF AYTDCIPQLM KMLFECSDER IDLELISFCI NLAANKRNVQ LICEGNGLKM LMKRALKLKD PLLMKMIRNI SQHDGPTKNL FIDYVGDLAA QISSDEEEEF VIECLGTLAN LTIPDLDWEL VLKEYKLVPF LKDKLKPGAA EDDLVLEVVI MIGTVSMDDS CAALLAKSGI IPALIELLNA QQEDDEFVCQ IIYVFYQMVF HQATRDVIIK ETQAPAYLID LMHDKNNEIR KVCDNTLDII AEYDEEWAKK IQSEKFRWHN SQWLEMVESR QLDESEQYLY GDDRIEPYIH EGDILERPDL FYNSDGLITS EGAISPDFFN DFHLQNGDVV GQHAFPGSLG MDGFGQPLGI LGRPATAYGF RPDEPYYYSF GSR
Expression Region 1-793
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat

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