Recombinant Mouse Optic atrophy 3 protein homolog (Opa3)

Code CSB-YP690364MO
MSDS
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Source Yeast
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Code CSB-EP690364MO
MSDS
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Source E.coli
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Code CSB-EP690364MO-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP690364MO
MSDS
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Source Baculovirus
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Code CSB-MP690364MO
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Opa3
Uniprot No.
Alternative Names
Opa3; Optic atrophy 3 protein homolog
Species
Mus musculus (Mouse)
Expression Region
1-179
Target Protein Sequence
MVVGAFPMAK LFYLGIRQVS KPLANRIKDA ARRSEFFKTY ICLPPAQLYH WVEMRTKMRI MGFRGTTIKP LNEEAAAELG AELLGEATIF IVGGGCLVLE YWRHQTQQRN KEEEQRAAWN ALQDEVGRLA LALEALQAQA QAMPSLSALE ELREELQEVR GQVCNAHCTS KCQAASSKK
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
May play some role in mitochondrial processes.
Gene References into Functions
  1. Opa3(L122P) mice displayed craniofacial abnormalities, including undergrowth of the lower mandible, accompanied in some individuals by cranial asymmetry and incisor malocclusion PMID: 27106103
  2. Opa3, a novel regulator of mitochondrial function, controls thermogenesis and abdominal fat mass in a mouse model for Costeff syndrome. PMID: 22869679
  3. Mutant Opa3 protein retains its mitochondrial localization and induces disrupted mitochondrial morphology. Opa3 accumulates in the lens. The results may reflect a slow turnover of Opa3 protein in vivo and may be important in normal lens physiology. PMID: 21613372
  4. to investigate the OPA3 function we have generated a novel ENU-induced mutant mouse carrying a missense mutation in the OPA3 gene. In the heterozygous state, the mice appear uncompromised. In the homozygous state mice display some of the features of MGA. PMID: 18222992
Subcellular Location
Mitochondrion.
Protein Families
OPA3 family
Database Links
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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