Recombinant Mouse Orexigenic neuropeptide QRFP (Qrfp)

Code CSB-YP807004MO
MSDS
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Source Yeast
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Code CSB-EP807004MO
MSDS
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Source E.coli
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Code CSB-EP807004MO-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP807004MO
MSDS
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Source Baculovirus
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Code CSB-MP807004MO
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Qrfp
Uniprot No.
Alternative Names
Qrfp; Orexigenic neuropeptide QRFP; P518) [Cleaved into: QRF-amide; Neuropeptide RF-amide; Pyroglutamylated arginine-phenylalanine-amide peptide)]
Species
Mus musculus (Mouse)
Expression Region
80-122
Target Protein Sequence
Q DGSSEAAGFL PADSEKASGP LGTLAEELSS YSRRKGGFSF RF
Protein Length
Cytoplasmic domain
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Stimulates feeding and grooming behavior, metabolic rate and locomotor activity and increases blood pressure. May have orexigenic activity. May promote aldosterone secretion by the adrenal gland.
Gene References into Functions
  1. QRFP is an important downstream mediator of the arcuate nucleus and regulates feeding behavior, mood, wakefulness and activity. PMID: 27835635
  2. 26RFa attenuates the hyperglycemia induced by a glucose load, potentiates insulin sensitivity, and increases plasma insulin concentrations. PMID: 25858563
  3. Macrophage-conditioned medium containing increased amounts of QRFP preserves adipogenesis in adipocytes. PMID: 24284825
  4. The present review discusses the role of QRFP in the regulation of feeding behavior, with emphasis on the intake of dietary fat. PMID: 23979792
  5. Results suggest that GPR103b and QRFP work in an autocrine/paracrine manner to regulate adipogenesis. PMID: 20534693
  6. Characterization and tissue distribution of SP9155 (GPR103) ligand. PMID: 12714592
  7. P518/26RFa is a neuropeptide that stimulates food intake in mice. PMID: 15891009
  8. Qrfp polymorphisms is associated with osteopenia PMID: 17869477

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Subcellular Location
Secreted.
Protein Families
RFamide neuropeptide family
Tissue Specificity
Expressed in the brain with highest levels in the periventricular hypothalamic nucleus and lateral hypothalamic areas. Expressed at moderate levels in the adrenal gland, eye, heart, intestine, liver, lung, kidney, mesenteric lymph node, ovary, placenta, P
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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