Recombinant Mouse PWWP domain-containing protein MUM1 (Mum1)

Code CSB-YP724934MO
MSDS
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Source Yeast
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Code CSB-EP724934MO
MSDS
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Source E.coli
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Code CSB-EP724934MO-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP724934MO
MSDS
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Source Baculovirus
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Code CSB-MP724934MO
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Mum1
Uniprot No.
Alternative Names
Pwwp3a; Mum1; PWWP domain-containing DNA repair factor 3A; PWWP3A; Mutated melanoma-associated antigen 1; MUM-1; PWWP domain-containing protein MUM1
Species
Mus musculus (Mouse)
Expression Region
1-682
Target Protein Sequence
MTDAKYVLCR WGKRLWPAKV LARTETSAKN KKKKEFFLDV QILSLKEKIQ VKSSAVEALQ KSHIENIAAF LASQNEVPAT PLEELTYRRS LRVALDVLNE RTSLSPESHP IEDGITLSQK EKTDADVASQ VSSAPSPSLL GEDGQAVVAQ CASKRRSEYS SKSLLPSSAL EDHLRCQVGP KTGLSESGAG DKSQDDSGLQ LDHGQESTTK KRQRNLGEKP TRRRRSESGL SKGESVLKSQ GQASSCVALA SPRPPSQTRD EEPCAGVKGC DWVKSSGNIR PLSASERSRG CPTKRPRLDG GQNPPTRQLG TRTVGAAPCP RSCSGEVTML CSAGAGDKPE EDPVSSEEST GFKSTHSLLE EEEEEEEEPP RILLYHEPRS FEVGMLVWLK YQKYPFWPAV VKSVRRRDKK ASVLFIEGNM NPKGRGITVS LRRLKHFDCK EKHALLDRAK EDFAQAIGWC VSLITDYRVR LGCGSFAGSF LEYYAADISY PVRKSIQQDV LGTRFPQLGK GDPEEPVGDS QLGQWRPCRK VLPDRSRAAR DRANQKLVEY IVKAKGAESH LRAILHSRKP SRWLKTFLSS SQCVTCMETY LEDEAQLDEV VEYLQGVCRD MDGQVPERGS GDRIRFILDV LLPEAIICAI SAVEAVDYKT AEQKYIRGPT LSYREKEIFD NELLEERNRR RR
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage.
Gene References into Functions
  1. results suggest that MUM1 plays roles in the progression of B-cell lymphoma/leukemia by regulating the expression of various genes including MIG. PMID: 15959530
Subcellular Location
Nucleus.
Protein Families
MUM1 family
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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