Recombinant Mouse Proto-oncogene FRAT1(Frat1)

Product Type Recombinant Protein
Uniprot No. P70339
Species Mus musculus (Mouse)
Gene Names Frat1
Protein Names Recommended name: Proto-oncogene FRAT1 Alternative name(s): Frequently rearranged in advanced T-cell lymphomas 1 Short name= FRAT-1
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Target Details This protein belongs to the GSK-3-binding protein family. The protein inhibits GSK-3-mediated phosphorylation of beta-catenin and positively regulates the Wnt signaling pathway. It may function in tumor progression and in lymphomagenesis.
HGNC 3944
MGI 109450
Function Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3. May play a role in tumor progression and collaborate with PIM1 and MYC in lymphomagenesis.
Involvement in disease Activation contributes to progression of mouse T-cell lymphomas (PubMed:9034327).
Subcellular Location Cytoplasm
Protein Families GSK-3-binding protein family
Tissue Specificity Highly expressed in testis. Lower level of expression in spleen, thymus and brain.
Database Links

KEGG: mmu:14296

UniGene: Mm.4573

Pathway Wnt signaling pathway

Product Details for Different Expression Systems

Product Name Recombinant Mouse Proto-oncogene FRAT1(Frat1),Yeast
Code CSB-YP008970MO
Size Pls inquiry other sizes
Source Yeast
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MPCRREEEEE AGDEAEGEED DDSFLLLQQS VTLGGSTDVD QLIVQIGETL QLDAAHDRPA SPCAAPGPPP PQVLAALPAD KTGTPARRLL RPTGSAETGN PAPPGAVRCV LGERGRVRGR SAPYCVAEIS PGASALPQQP GLDGPPGTGK LSTPQPLSGP CRRGWLRNAA ASRRLQQRRG SQPETRTGDD DDPHRLLQQL VLSGNLIKEA VRRLHSRQLQ LHAKLPAHPF LGPLSAPVHE PPSPGSPRAA CSDPGAFMGR AQLRTGDDLL VPGS
Expression Region 1-274
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
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Product Name Recombinant Mouse Proto-oncogene FRAT1(Frat1),E.coli
Code CSB-EP008970MO
Size Pls inquiry other sizes
Source E.coli
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-SUMO-tagged and C-terminal Myc-tagged
N-terminal His-B2M-tagged and C-terminal Myc-tagged
N-terminal His-GST-tagged and C-terminal Myc-tagged
N-terminal His-tagged
N-terminal His-SUMO-tagged
N-terminal His-B2M-tagged
N-terminal His-GST-tagged
N-terminal GST-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MPCRREEEEE AGDEAEGEED DDSFLLLQQS VTLGGSTDVD QLIVQIGETL QLDAAHDRPA SPCAAPGPPP PQVLAALPAD KTGTPARRLL RPTGSAETGN PAPPGAVRCV LGERGRVRGR SAPYCVAEIS PGASALPQQP GLDGPPGTGK LSTPQPLSGP CRRGWLRNAA ASRRLQQRRG SQPETRTGDD DDPHRLLQQL VLSGNLIKEA VRRLHSRQLQ LHAKLPAHPF LGPLSAPVHE PPSPGSPRAA CSDPGAFMGR AQLRTGDDLL VPGS
Expression Region 1-274
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Mouse Proto-oncogene FRAT1(Frat1),Baculovirus
Code CSB-BP008970MO
Size Pls inquiry other sizes
Source Baculovirus
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MPCRREEEEE AGDEAEGEED DDSFLLLQQS VTLGGSTDVD QLIVQIGETL QLDAAHDRPA SPCAAPGPPP PQVLAALPAD KTGTPARRLL RPTGSAETGN PAPPGAVRCV LGERGRVRGR SAPYCVAEIS PGASALPQQP GLDGPPGTGK LSTPQPLSGP CRRGWLRNAA ASRRLQQRRG SQPETRTGDD DDPHRLLQQL VLSGNLIKEA VRRLHSRQLQ LHAKLPAHPF LGPLSAPVHE PPSPGSPRAA CSDPGAFMGR AQLRTGDDLL VPGS
Expression Region 1-274
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Mouse Proto-oncogene FRAT1(Frat1),Mammalian cell
Code CSB-MP008970MO
Size Pls inquiry other sizes
Source Mammalian cell
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MPCRREEEEE AGDEAEGEED DDSFLLLQQS VTLGGSTDVD QLIVQIGETL QLDAAHDRPA SPCAAPGPPP PQVLAALPAD KTGTPARRLL RPTGSAETGN PAPPGAVRCV LGERGRVRGR SAPYCVAEIS PGASALPQQP GLDGPPGTGK LSTPQPLSGP CRRGWLRNAA ASRRLQQRRG SQPETRTGDD DDPHRLLQQL VLSGNLIKEA VRRLHSRQLQ LHAKLPAHPF LGPLSAPVHE PPSPGSPRAA CSDPGAFMGR AQLRTGDDLL VPGS
Expression Region 1-274
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat

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