Recombinant Mouse Rab GTPase-binding effector protein 2 (Rabep2)

Code CSB-YP845986MO
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Source Yeast
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Code CSB-EP845986MO
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Source E.coli
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Code CSB-EP845986MO-B
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP845986MO
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Source Baculovirus
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Code CSB-MP845986MO
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Rabep2
Uniprot No.
Alternative Names
Rabep2; Rabpt5b; Rab GTPase-binding effector protein 2; Rabaptin-5beta
Species
Mus musculus (Mouse)
Expression Region
1-554
Target Protein Sequence
MAAAPATLAL DPQPQEKQKD ASESSELSRL RAELAGALAE METMKAVAEV SESTKAEAVA AVQRQCQEEV ASLQAILKDS ISSYETQIAA LKQERQQQQQ DFEEKDRELG HLKQLLARAH PLDSLEKQME KAHEDSEKLR EIVLPMEQEI TELKGKLQRA EELIQEIQRR PRQPASLHGS TELLPLSRNP SPPLEPLEEP SGDAGPAAEA FAHNCDDSAS ISSFSLGGAA GSASLRGPQG LSPEQEETAS LVSTGTLVPE GIFLPPPGYQ LVPDSQWEQL QVEGRQLQKE LESVSRERDE LQEGLRRSNE DCAKQMQVLL AQVQNSEQLL RTLQGTVSQA QERVQLQMAE LATSHKCLSQ EVKRLNEENQ GLRAEQLPSS ALQGSEQRED QDEALPSSIQ ELHLLVQNTR QQARARQQAQ EHEAERLRIE IVKLREALDE ETAAKASLER QLRVQREETD VLEASLCSLR IETERVQQEQ RKAQLTDLLS EQRAKTLRLQ AELETSEQVQ RDFVRLSQAL QVRLERIRQA ETLQQVRSIL DEAPLRDIRD IKDS
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Plays a role in membrane trafficking and in homotypic early endosome fusion. Participates in arteriogenesis by regulating vascular endothelial growth factor receptor 2/VEGFR2 cell surface expression and endosomal trafficking. By interacting with SDCCAG8, localizes to centrosomes and plays a critical role in ciliogenesis.
Gene References into Functions
  1. SDCCAG8 interacts with proteins of the centriolar satellites (OFD1, AZI1), of the endosomal sorting complex (RABEP2, ERC1), and with non-muscle myosin motor proteins (MYH9, MYH10, MYH14) at the centrosome. PMID: 27224062
  2. Naturally occurring variants of Rabep2 are major determinants of variation in collateral extent and stroke severity in mice. PMID: 27811335
Subcellular Location
Cytoplasm. Early endosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, cilium basal body.
Protein Families
Rabaptin family
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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