Recombinant Mouse Selenoprotein P(Sepp1)

Product Type Recombinant Protein
Uniprot No. P70274
Species Mus musculus (Mouse)
Gene Names Selenop
Protein Names Recommended name: Selenoprotein P Short name= SeP Alternative name(s): Plasma selenoprotein P
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Target Details This gene encodes a selenoprotein containing multiple selenocysteine (Sec) residues, which are encoded by the UGA codon that normally signals translation termination. The 3 UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This selenoprotein is an extracellular glycoprotein, and is unusual in that it contains 10 Sec residues per polypeptide. It is a heparin-binding protein that appears to be associated with endothelial cells, and has been implicated to function as an antioxidant in the extracellular space. Several transcript variants, encoding either the same or different isoform, have been found for this gene.
Function Might be responsible for some of the extracellular antioxidant defense properties of selenium or might be involved in the transport of selenium (By similarity). May supply selenium to tissues such as brain and testis.
Subcellular Location Secreted
Protein Families Selenoprotein P family
Tissue Specificity In the kidney, expressed in the cortex with no expression observed in the medulla (at protein level) (PubMed:18174160). Expressed by the liver and secreted in plasma (PubMed:9687017).
Database Links

KEGG: mmu:20363

STRING: 10090.ENSMUSP00000081004

UniGene: Mm.392203

Product Details for Different Expression Systems

Product Name Recombinant Mouse Selenoprotein P(Sepp1),Yeast
Code CSB-YP021018MO
Size Pls inquiry other sizes
Source Yeast
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence E SQGQSSACYK APEWYIGDQN PMLNSEGKVT VVALLQASUY LCLLQASRLE DLRIKLESQG YFNISYIVVN HQGSPSQLKH SHLKKQVSEH IAVYRQEEDG IDVWTLLNGN KDDFLIYDRC GRLVYHLGLP YSFLTFPYVE EAIKIAYCEE RCGNCNLTSL EDEDFCKTVT SATANKTAEP SEAHSHHKHH NKHGQEHLGS SKPSENQQPG PSETTLPPSG LHHHHRHRGQ HRQGHLESUD TTASEGLHLS LAQRKLURRG CINQLLCKLS KESEAAPSSC CCHCRHLIFE KSGSAIAUQC AENLPSLCSU QGLFAEEKVT ESCQCRSPPA AUQNQPMNPM EANPNUSUDN QTRKUKUHSN
Expression Region 20-380
Protein Description Full Length of Mature Protein
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
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Product Name Recombinant Mouse Selenoprotein P(Sepp1),E.coli
Code CSB-EP021018MO
Size Pls inquiry other sizes
Source E.coli
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-SUMO-tagged and C-terminal Myc-tagged
N-terminal His-B2M-tagged and C-terminal Myc-tagged
N-terminal His-GST-tagged and C-terminal Myc-tagged
N-terminal His-tagged
N-terminal His-SUMO-tagged
N-terminal His-B2M-tagged
N-terminal His-GST-tagged
N-terminal GST-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence E SQGQSSACYK APEWYIGDQN PMLNSEGKVT VVALLQASUY LCLLQASRLE DLRIKLESQG YFNISYIVVN HQGSPSQLKH SHLKKQVSEH IAVYRQEEDG IDVWTLLNGN KDDFLIYDRC GRLVYHLGLP YSFLTFPYVE EAIKIAYCEE RCGNCNLTSL EDEDFCKTVT SATANKTAEP SEAHSHHKHH NKHGQEHLGS SKPSENQQPG PSETTLPPSG LHHHHRHRGQ HRQGHLESUD TTASEGLHLS LAQRKLURRG CINQLLCKLS KESEAAPSSC CCHCRHLIFE KSGSAIAUQC AENLPSLCSU QGLFAEEKVT ESCQCRSPPA AUQNQPMNPM EANPNUSUDN QTRKUKUHSN
Expression Region 20-380
Protein Description Full Length of Mature Protein
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Mouse Selenoprotein P(Sepp1),Baculovirus
Code CSB-BP021018MO
Size Pls inquiry other sizes
Source Baculovirus
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence E SQGQSSACYK APEWYIGDQN PMLNSEGKVT VVALLQASUY LCLLQASRLE DLRIKLESQG YFNISYIVVN HQGSPSQLKH SHLKKQVSEH IAVYRQEEDG IDVWTLLNGN KDDFLIYDRC GRLVYHLGLP YSFLTFPYVE EAIKIAYCEE RCGNCNLTSL EDEDFCKTVT SATANKTAEP SEAHSHHKHH NKHGQEHLGS SKPSENQQPG PSETTLPPSG LHHHHRHRGQ HRQGHLESUD TTASEGLHLS LAQRKLURRG CINQLLCKLS KESEAAPSSC CCHCRHLIFE KSGSAIAUQC AENLPSLCSU QGLFAEEKVT ESCQCRSPPA AUQNQPMNPM EANPNUSUDN QTRKUKUHSN
Expression Region 20-380
Protein Description Full Length of Mature Protein
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Mouse Selenoprotein P(Sepp1),Mammalian cell
Code CSB-MP021018MO
Size Pls inquiry other sizes
Source Mammalian cell
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence E SQGQSSACYK APEWYIGDQN PMLNSEGKVT VVALLQASUY LCLLQASRLE DLRIKLESQG YFNISYIVVN HQGSPSQLKH SHLKKQVSEH IAVYRQEEDG IDVWTLLNGN KDDFLIYDRC GRLVYHLGLP YSFLTFPYVE EAIKIAYCEE RCGNCNLTSL EDEDFCKTVT SATANKTAEP SEAHSHHKHH NKHGQEHLGS SKPSENQQPG PSETTLPPSG LHHHHRHRGQ HRQGHLESUD TTASEGLHLS LAQRKLURRG CINQLLCKLS KESEAAPSSC CCHCRHLIFE KSGSAIAUQC AENLPSLCSU QGLFAEEKVT ESCQCRSPPA AUQNQPMNPM EANPNUSUDN QTRKUKUHSN
Expression Region 20-380
Protein Description Full Length of Mature Protein
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Still Have Questions? Leave a Message or Start an on-line Chat

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