Recombinant Mouse Tropomodulin-3 (Tmod3)

Code CSB-YP872826MO
MSDS
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Source Yeast
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Code CSB-EP872826MO
MSDS
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Source E.coli
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Code CSB-EP872826MO-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP872826MO
MSDS
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Source Baculovirus
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Code CSB-MP872826MO
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Tmod3
Uniprot No.
Alternative Names
Tmod3; Tropomodulin-3; Ubiquitous tropomodulin; U-Tmod
Species
Mus musculus (Mouse)
Expression Region
1-352
Target Protein Sequence
MALPFRKDLG DYKDLDEDEL LGKLSESELK QLETVLDDLD PENALLPAGF RQKNQTSKSA TGPFDRERLL SYLEKQALEH KDRDDYVPYT GEKKGKIFIP KQKPAQTLTE ETISLDPELE EALTSASDTE LCDLAAILGM HNLIADTPFC DVLGSSNGVN QERFPNVVKG EKILPVFDEP PNPTNVEESL KRIRENDARL VEVNLNNIKN IPIPTLKDFA KTLEANTHVK HFSLAATRSN DPVAVAFADM LKVNKTLKSL NMESNFITGA GVLALIDALR DNETLMELKI DNQRQQLGTS VELEMAKMLE ENTNILKFGY QFTQQGPRTR AANAITKNND LVRKRRIEGD HQ
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton.
Gene References into Functions
  1. Tmod3 plays crucial roles in oocyte maturation PMID: 27374327
  2. Loss of TMOD3 is associated with hemorrhage, defect in actin polymerization, organization and platelet biogenesis. PMID: 25964668
  3. Tmod1 and Tmod3 showed somewhat different tropomyosin-binding site utilization. PMID: 24922351
  4. Tmod3-/- embryos are defective in definitive erythropoiesis with reduced progenitors, impaired terminal differentiation, and enucleation. PMID: 24159174
  5. Western blots of Tmod1-null RBCs confirm the absence of Tmod1 and show the presence of Tmod3, which is normally not present in RBCs. PMID: 20585041
  6. Tmod3 and -4 localize to pointed ends in Tmod1-null adult muscle PMID: 20368620

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Subcellular Location
Cytoplasm, cytoskeleton.
Protein Families
Tropomodulin family
Tissue Specificity
Ubiquitous.
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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