Recombinant Mouse Uncharacterized protein C17orf96 homolog

Code CSB-YP749253MO
MSDS
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Source Yeast
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Code CSB-EP749253MO
MSDS
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Source E.coli
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Code CSB-EP749253MO-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP749253MO
MSDS
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Source Baculovirus
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Code CSB-MP749253MO
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Epop
Uniprot No.
Alternative Names
Epop; E13Elongin BC and Polycomb repressive complex 2-associated protein; Embryonic stem cell-specific PRC2 subunit p48; ES cell-specific PRC2 subunit p48; esPRC2p48
Species
Mus musculus (Mouse)
Expression Region
1-369
Target Protein Sequence
METLCPPPRL AVPASPRGSP CSPTPLKPRR GTPEFSPLCL RALAFCALAK PRPSSLGLGP GELAPRTPVL LGPPASPCTG GWAADGLKHL GGQAGRPSDV SSPAREDADV AVCPGGGEEE EGGGGFPHFG AGSCAPPGRC PAPLRPQDSP TNPAWSPPRP ARGLDAASSP PLEPGSPPPS PPAGLSPEPA PSEQPVPASE APGGGDPAPT APEAPALSPS TADAAPDPPR DLRQEHFNRL IRRSKLWCYA KGFALDTPSL RRGPERPAAK ARGAAKKRRR PAPPPPSVQP RRPVPTLPTS STFSLLDCFP CPPALVVEEN GDLGPASSLR LQGDAKPPPA HPLWKWQMGG PAVPEPPGLK SWWVNLEEL
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Scaffold protein that serves as a bridging partner between the PRC2/EZH2 complex and the elongin BC complex: required to fine-tune the transcriptional status of Polycomb group (PcG) target genes in embryonic stem cells (ESCs). Plays a key role in genomic regions that display both active and repressive chromatin properties in pluripotent stem cells by sustaining low level expression at PcG target genes: acts by recruiting the elongin BC complex, thereby restricting excessive activity of the PRC2/EZH2 complex. Interaction with USP7 promotes deubiquitination of H2B at promoter sites. Acts as a regulator of neuronal differentiation.
Gene References into Functions
  1. Results demonstrated that E130012A19Rik (E13), is a protein-coding gene implicated in regulating the commitment towards the different neuronal subtypes and glia cells. PMID: 23180766
  2. these studies identify JARID2, MTF2, and esPRC2p48 as important regulatory subunits of PRC2 in ES cells and reveal critical functions of these subunits. PMID: 21732481
Subcellular Location
Nucleus. Chromosome.
Tissue Specificity
Highly expressed in embryonic stem cells (ESCs) during embryogenesis and in the adult brain.
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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