Recombinant Mouse WD repeat-containing protein 91 (Wdr91)

Code CSB-YP756009MO
MSDS
Size Pls inquire
Source Yeast
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Code CSB-EP756009MO
MSDS
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Source E.coli
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Code CSB-EP756009MO-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP756009MO
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP756009MO
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Wdr91
Uniprot No.
Alternative Names
Wdr91; WD repeat-containing protein 91
Species
Mus musculus (Mouse)
Expression Region
1-748
Target Protein Sequence
MAEAVERTDE LVREYLLFRG FTHTLRQLDA EIKADKEKGF RVDKIVDQLQ QLMQVYDLAA LRDYWSYLER RLFSRLEDIY RPTINKLKTS LFRFYLVYTI QTNRNDKAQE FFAKQATELQ NQAEWKDWFV LPFLPSPDTN PTFATYFSRQ WADTFIISLH NFLSVLFQCM PVPVILNFDA ECQRTNQVQE ENEVLRQKLF ALQAEIHRLK KEEQQQEEEA AALVQHKLPP YVSSMDRLGD SELALVCSQR PASLSQSPRV GFLSSLLPQS KKSPSRLSPA QGPPQAQSSA KKDSFSSQAT KGKDSVPGAK DGKSLLSGPV PGEASWTHQR QRRLQDHGKE RRELLSTSSS QSQCAERKPE VSGAEAEPCL ELHMGPVEVL ARVSTAGSEG DRPEQPFIVL SQEEYGEHHS SIMHCRVDCS GRRVASLDVD GVIKVWSFNP IMQTKASSIS KSPLLSLEWA TKRDRLLLLG SGVGTVRLYD TEAKKNLCEI NINDDMPRIL SLACSPNGAS FVCSAAAPSL TSQTDSSAPD IGSKGMNQVP GKLLLWDTKT MKQQLQFSLD PEPIAINCTA FNHNGNLLVT GAADGVIRLF DMQQHECAMS WKAHCGEVYS VEFSCDENAV YSIGEDRKFI QWNIHKSGLK VSESNLPSDA TGPFVLSGYS GYKQVQVPRG RLFAFDSEGN YMLTCSATGG LIYKLGSEEK VLENCLSLGG HRAPVVTVDW STAMDCGTCL TASMDGKIKL TTLLAHKL
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Functions as a negative regulator of the PI3 kinase/PI3K activity associated with endosomal membranes via BECN1, a core subunit of the PI3K complex. By modifying the phosphatidylinositol 3-phosphate/PtdInsP3 content of endosomal membranes may regulate endosome fusion, recycling, sorting and early to late endosome transport. It is for instance, required for the delivery of cargos like BST2/tetherin from early to late endosome and thereby participates indirectly to their degradation by the lysosome. May play a role in meiosis.
Gene References into Functions
  1. WDR91 serves as a Rab7 effector that is essential for neuronal development by facilitating endosome conversion in the endosome-lysosome pathway. PMID: 28860274
Subcellular Location
Early endosome membrane; Peripheral membrane protein. Late endosome membrane.
Protein Families
WD repeat WDR91 family
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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