Recombinant Mouse Xaa-Pro dipeptidase (Pepd)

Code CSB-YP604737MO
MSDS
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Source Yeast
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Code CSB-EP604737MO
MSDS
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Source E.coli
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Code CSB-EP604737MO-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP604737MO
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP604737MO
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Pepd
Uniprot No.
Alternative Names
Pepd; Pep4Xaa-Pro dipeptidase; X-Pro dipeptidase; EC 3.4.13.9; Imidodipeptidase; Peptidase 4; Peptidase D; Proline dipeptidase; Prolidase
Species
Mus musculus (Mouse)
Expression Region
2-493
Target Protein Sequence
ASTVRPSFS LGNETLKVPL ALFALNRQRL CERLRKNGAV QAASAVVLQG GEEMQRYCTD TSIIFRQESF FHWAFGVVES GCYGVIDVDT GKSTLFVPRL PDSYATWMGK IHSKEYFKEK YAVDDVQYTD EIASVLTSRN PSVLLTLRGV NTDSGSVCRE ASFEGISKFN VNNTILHPEI VECRVFKTDM ELEVLRYTNR ISSEAHREVM KAVKVGMKEY EMESLFQHYC YSRGGMRHTS YTCICCSGEN AAVLHYGHAG APNDRTIKDG DICLFDMGGE YYCFASDITC SFPANGKFTE DQKAIYEAVL RSCRTVMSTM KPGVWWPDMH RLADRIHLEE LARIGLLSGS VDAMLQVHLG AVFMPHGLGH FLGLDVHDVG GYPEGVERID EPGLRSLRTA RHLEPGMVLT VEPGIYFIDH LLDQALADPA QACFFNQEVL QRFRNFGGVR IEEDVVVTDS GMELLTCVPR TVEEIEACMA GCDKASVPFS GQK
Protein Length
Full Length of Mature Protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Splits dipeptides with a prolyl or hydroxyprolyl residue in the C-terminal position. Plays an important role in collagen metabolism because of the high level of iminoacids in collagen.
Gene References into Functions
  1. The findings identify peptidase D, an ubiquitously expressed intracellular peptidase, as a potential novel marker of colitis. PMID: 28323866
  2. PEPD is a ligand of EGFR and presents a novel mechanism of EGFR activation PMID: 23212918
  3. The dark-like mutation causes cardiomyocyte hypertrophy due to loss-of-function of peptidase d (Pepd). PMID: 21472842
  4. NO stimulates prolidase activity by increasing serine/threonine phosphorylation through PKG-cGMP pathway PMID: 16167338
Protein Families
Peptidase M24B family, Eukaryotic-type prolidase subfamily
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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