Recombinant Pig C-reactive protein (CRP)

Code CSB-YP005991PI
MSDS
Size Pls inquire
Source Yeast
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Code CSB-EP005991PI
MSDS
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Source E.coli
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Code CSB-EP005991PI-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP005991PI
MSDS
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Source Baculovirus
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Code CSB-MP005991PI
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
CRP
Uniprot No.
Alternative Names
CRP; PTX1C-reactive protein
Species
Sus scrofa (Pig)
Expression Region
20-222
Target Protein Sequence
Q TDMIGKAFVF PKESENSYVS LTARLTKPLT AFTVCLRVYT DLNRDYSLFS YATKTQYNEI LLFRGKTAVY SISVGGADVV FKPHQSSEPM HFCMTWESTS GITELWVDGK PMVRRSLKRG YSLGTQASII LGQEQDAFAG GFEKNQCLVG DIGDVNMWDY VLSPEEINTV YAGGTFSPNV LNWRALRYEM SGEVYVKPQL WP
Protein Length
Full Length of Mature Protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.
Gene References into Functions
  1. Enhanced external counterpulsation decreased C-reactive protein and increased flow-mediated dilation in hypercholesterolemia. PMID: 22681602
  2. serum C-reactive protein correlates with macrophage accumulation and coronary artery disease in hypercholesterolemic pigs PMID: 12754176
  3. CRP inhibits endothelium-dependent NO-mediated dilation in coronary arterioles by producing superoxide from NAD(P)H oxidase via p38 kinase activation. PMID: 15718491
  4. The present study shows that elevated levels of serum CRP and IL-10 were associated with porcine circovirus type 2-infected piglets that subsequently developed severe PMWS. (postweaning multisystemic wasting syndrome) PMID: 16817761
  5. These data suggest that CRP might play a pathogenic role in the development of myointimal hyperplasia in polytetrafluoroethylene grafts. PMID: 17510097
  6. myocardial infarction induced proinflammatory gene and protein expression in peripheral blood mononuclear cells of tissue factor cyclo-oxygenase-2, monocyte chemoattractant protein-1 and CRP PMID: 19036073
  7. CRP stimulates superoxide production and the subsequent formation of peroxynitrite from basal released nitric oxide compromises PGI(2) synthesis. PMID: 19410579
  8. Data show that during posttranplant obliterative bronchiolitis development, CRP is localized in inflammatory cells, myofibroblasts and endothelial cells probably as a part of the local inflammatory response. PMID: 19503785

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Subcellular Location
Secreted.
Protein Families
Pentraxin family
Tissue Specificity
Found in plasma.
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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