||Contributes to phagocytic removal of apoptotic cells in many tissues. Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization (By similarity). Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction.
||Membrane, Peripheral membrane protein, Secreted, Cytoplasmic vesicle, secretory vesicle, acrosome membrane, Peripheral membrane protein
||Mammary epithelial cell surfaces and spermatozoan. Also present in testis, epididymis, uterus, adrenal gland, tonsil, muscle, heart, lymphatic gland, thymus and kidney but not spleen, liver, lung or brain.