Recombinant Pig Mineralocorticoid receptor(NR3C2)

Product Type Recombinant Protein
Uniprot No. P79404
Species Sus scrofa (Pig)
Gene Names NR3C2
Protein Names Recommended name: Mineralocorticoid receptor Short name= MR Alternative name(s): Nuclear receptor subfamily 3 group C member 2
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Target Details This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants.
Function Receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. Binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels (By similarity).
Subcellular Location Cytoplasm, Nucleus, Endoplasmic reticulum membrane, Peripheral membrane protein
Protein Families Nuclear hormone receptor family, NR3 subfamily
Database Links

STRING: 9823.ENSSSCP00000019392

UniGene: Ssc.1868

Product Details for Different Expression Systems

Product Name Recombinant Pig Mineralocorticoid receptor(NR3C2),Yeast
Code CSB-YP016061PI
Size Pls inquiry other sizes
Source Yeast
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence QYSWMCLSSF ALSWRSYKHT NSQFLYFAPD LVFNEEKMHQ SAMYELCQGM HQISLQFVRL QLTFEEYTIM KVLLLLSTIP KDGLKSQAAF EEMRTNYIKE LRKMVTRCPN NSGQSWQRFY QLTKLLDSMH DLVSDLLEFC FYTFRESQAL KVEFPRCWWR SSPT
Expression Region 1-164
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
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Product Name Recombinant Pig Mineralocorticoid receptor(NR3C2),E.coli
Code CSB-EP016061PI
Size Pls inquiry other sizes
Source E.coli
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-SUMO-tagged and C-terminal Myc-tagged
N-terminal His-B2M-tagged and C-terminal Myc-tagged
N-terminal His-GST-tagged and C-terminal Myc-tagged
N-terminal His-tagged
N-terminal His-SUMO-tagged
N-terminal His-B2M-tagged
N-terminal His-GST-tagged
N-terminal GST-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence QYSWMCLSSF ALSWRSYKHT NSQFLYFAPD LVFNEEKMHQ SAMYELCQGM HQISLQFVRL QLTFEEYTIM KVLLLLSTIP KDGLKSQAAF EEMRTNYIKE LRKMVTRCPN NSGQSWQRFY QLTKLLDSMH DLVSDLLEFC FYTFRESQAL KVEFPRCWWR SSPT
Expression Region 1-164
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Pig Mineralocorticoid receptor(NR3C2),Baculovirus
Code CSB-BP016061PI
Size Pls inquiry other sizes
Source Baculovirus
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence QYSWMCLSSF ALSWRSYKHT NSQFLYFAPD LVFNEEKMHQ SAMYELCQGM HQISLQFVRL QLTFEEYTIM KVLLLLSTIP KDGLKSQAAF EEMRTNYIKE LRKMVTRCPN NSGQSWQRFY QLTKLLDSMH DLVSDLLEFC FYTFRESQAL KVEFPRCWWR SSPT
Expression Region 1-164
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Pig Mineralocorticoid receptor(NR3C2),Mammalian cell
Code CSB-MP016061PI
Size Pls inquiry other sizes
Source Mammalian cell
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence QYSWMCLSSF ALSWRSYKHT NSQFLYFAPD LVFNEEKMHQ SAMYELCQGM HQISLQFVRL QLTFEEYTIM KVLLLLSTIP KDGLKSQAAF EEMRTNYIKE LRKMVTRCPN NSGQSWQRFY QLTKLLDSMH DLVSDLLEFC FYTFRESQAL KVEFPRCWWR SSPT
Expression Region 1-164
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat

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