Recombinant Pig S-arrestin(SAG)

Product Type Recombinant Protein
Uniprot No. P79260
Species Sus scrofa (Pig)
Gene Names SAG
Protein Names Recommended name: S-arrestin Alternative name(s): 48 kDa protein Retinal S-antigen Short name= S-AG Rod photoreceptor arrestin
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Target Details Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. S-arrestin, also known as S-antigen, is a major soluble photoreceptor protein that is involved in desensitization of the photoactivated transduction cascade. It is expressed in the retina and the pineal gland and inhibits coupling of rhodopsin to transducin in vitro. Additionally, S-arrestin is highly antigenic, and is capable of inducing experimental autoimmune uveoretinitis. Mutations in this gene have been associated with Oguchi disease, a rare autosomal recessive form of night blindness.
HGNC 3368
RGD 619725
MGI 1202295
Function Binds to photoactivated, phosphorylated RHO and terminates RHO signaling via G-proteins by competing with G-proteins for the same binding site on RHO. May play a role in preventing light-dependent degeneration of retinal photoreceptor cells.
Subcellular Location Cell projection, cilium, photoreceptor outer segment, Membrane, Peripheral membrane protein
Protein Families Arrestin family
Tissue Specificity Retina pigment epithelium.
Database Links

KEGG: ssc:397151

STRING: 9823.ENSSSCP00000017271

UniGene: Ssc.296

Product Details for Different Expression Systems

Product Name Recombinant Pig S-arrestin(SAG),Yeast
Code CSB-YP020669PI
Size Pls inquiry other sizes
Source Yeast
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MAANVQASKS TPNHVIFKKT SRDKSVTIYL GKRDYIDHVD QVEPVDGVVL VDPELVKGKR VYVSLTCAFR YGQEDIDVIG LSFRRDLYFS QVQVFPPVGA ASQTKLQESL IKKLGGHTYP FLLTFPDYLP CSVMLQPAPQ DVGKCCGVDF EVKAFATDSA DTGEDKIPKK SSVRLLIRKV QHAPLEMGPQ PHAEAAWQFF MSDKPLHLTV SLSKELYYHG EPIPVTVTVT NNTEKTVKKI KALVEQVANV VLYSSDYYIK PVATEETQQK VPPNSTLTTT LTLVPLLANN RERRGIADGK IKHEDTNLAS STIIKEGMDK TIMGILVSYQ IKVQLTVSGL LGELTSSEVA TEVPFRLMHP QPEDPEAMDS FQDENFVFEE FARQNLKDAG ELKEEKTDQE AAAHE
Expression Region 1-405
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
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Product Name Recombinant Pig S-arrestin(SAG),E.coli
Code CSB-EP020669PI
Size Pls inquiry other sizes
Source E.coli
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-SUMO-tagged and C-terminal Myc-tagged
N-terminal His-B2M-tagged and C-terminal Myc-tagged
N-terminal His-GST-tagged and C-terminal Myc-tagged
N-terminal His-tagged
N-terminal His-SUMO-tagged
N-terminal His-B2M-tagged
N-terminal His-GST-tagged
N-terminal GST-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MAANVQASKS TPNHVIFKKT SRDKSVTIYL GKRDYIDHVD QVEPVDGVVL VDPELVKGKR VYVSLTCAFR YGQEDIDVIG LSFRRDLYFS QVQVFPPVGA ASQTKLQESL IKKLGGHTYP FLLTFPDYLP CSVMLQPAPQ DVGKCCGVDF EVKAFATDSA DTGEDKIPKK SSVRLLIRKV QHAPLEMGPQ PHAEAAWQFF MSDKPLHLTV SLSKELYYHG EPIPVTVTVT NNTEKTVKKI KALVEQVANV VLYSSDYYIK PVATEETQQK VPPNSTLTTT LTLVPLLANN RERRGIADGK IKHEDTNLAS STIIKEGMDK TIMGILVSYQ IKVQLTVSGL LGELTSSEVA TEVPFRLMHP QPEDPEAMDS FQDENFVFEE FARQNLKDAG ELKEEKTDQE AAAHE
Expression Region 1-405
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
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Product Name Recombinant Pig S-arrestin(SAG),Baculovirus
Code CSB-BP020669PI
Size Pls inquiry other sizes
Source Baculovirus
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MAANVQASKS TPNHVIFKKT SRDKSVTIYL GKRDYIDHVD QVEPVDGVVL VDPELVKGKR VYVSLTCAFR YGQEDIDVIG LSFRRDLYFS QVQVFPPVGA ASQTKLQESL IKKLGGHTYP FLLTFPDYLP CSVMLQPAPQ DVGKCCGVDF EVKAFATDSA DTGEDKIPKK SSVRLLIRKV QHAPLEMGPQ PHAEAAWQFF MSDKPLHLTV SLSKELYYHG EPIPVTVTVT NNTEKTVKKI KALVEQVANV VLYSSDYYIK PVATEETQQK VPPNSTLTTT LTLVPLLANN RERRGIADGK IKHEDTNLAS STIIKEGMDK TIMGILVSYQ IKVQLTVSGL LGELTSSEVA TEVPFRLMHP QPEDPEAMDS FQDENFVFEE FARQNLKDAG ELKEEKTDQE AAAHE
Expression Region 1-405
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Pig S-arrestin(SAG),Mammalian cell
Code CSB-MP020669PI
Size Pls inquiry other sizes
Source Mammalian cell
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MAANVQASKS TPNHVIFKKT SRDKSVTIYL GKRDYIDHVD QVEPVDGVVL VDPELVKGKR VYVSLTCAFR YGQEDIDVIG LSFRRDLYFS QVQVFPPVGA ASQTKLQESL IKKLGGHTYP FLLTFPDYLP CSVMLQPAPQ DVGKCCGVDF EVKAFATDSA DTGEDKIPKK SSVRLLIRKV QHAPLEMGPQ PHAEAAWQFF MSDKPLHLTV SLSKELYYHG EPIPVTVTVT NNTEKTVKKI KALVEQVANV VLYSSDYYIK PVATEETQQK VPPNSTLTTT LTLVPLLANN RERRGIADGK IKHEDTNLAS STIIKEGMDK TIMGILVSYQ IKVQLTVSGL LGELTSSEVA TEVPFRLMHP QPEDPEAMDS FQDENFVFEE FARQNLKDAG ELKEEKTDQE AAAHE
Expression Region 1-405
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat

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