Recombinant Rabbit C-C motif chemokine 2(CCL2)

Product Type Recombinant Protein
Uniprot No. P28292
Species Oryctolagus cuniculus (Rabbit)
Gene Names CCL2
Protein Names Recommended name: C-C motif chemokine 2 Alternative name(s): Monocyte chemoattractant protein 1 Monocyte chemotactic protein 1 Short name= MCP-1 Small-inducible cytokine A2
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Target Details This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. This protein is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.
Function Chemotactic factor that attracts monocytes, but not neutrophils.
Subcellular Location Secreted
Protein Families Intercrine beta (chemokine CC) family
Database Links

KEGG: ocu:100009130

STRING: 9986.ENSOCUP00000015636

UniGene: Ocu.1921

Pathway Chemokine signaling pathway
TNF signaling pathway
IL-17 signaling pathway
NOD-like receptor signaling pathway
AGE-RAGE signaling pathway in diabetic complications

Product Details for Different Expression Systems

Product Name Recombinant Rabbit C-C motif chemokine 2(CCL2),Yeast
Code CSB-YP004783RB
Size Pls inquiry other sizes
Source Yeast
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence QPDAVNS PVTCCYTFTN KTISVKRLMS YRRINSTKCP KEAVIFMTKL AKGICADPKQ KWVQDAIANL DKKMQTPKTL TSYSTTQEHT TNLSSTRTPS TTTSL
Expression Region 24-125
Protein Description Full Length of Mature Protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Rabbit C-C motif chemokine 2(CCL2),E.coli
Code CSB-EP004783RB
Size Pls inquiry other sizes
Source E.coli
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-SUMO-tagged and C-terminal Myc-tagged
N-terminal His-B2M-tagged and C-terminal Myc-tagged
N-terminal His-GST-tagged and C-terminal Myc-tagged
N-terminal His-tagged
N-terminal His-SUMO-tagged
N-terminal His-B2M-tagged
N-terminal His-GST-tagged
N-terminal GST-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence QPDAVNS PVTCCYTFTN KTISVKRLMS YRRINSTKCP KEAVIFMTKL AKGICADPKQ KWVQDAIANL DKKMQTPKTL TSYSTTQEHT TNLSSTRTPS TTTSL
Expression Region 24-125
Protein Description Full Length of Mature Protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Rabbit C-C motif chemokine 2(CCL2),Baculovirus
Code CSB-BP004783RB
Size Pls inquiry other sizes
Source Baculovirus
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence QPDAVNS PVTCCYTFTN KTISVKRLMS YRRINSTKCP KEAVIFMTKL AKGICADPKQ KWVQDAIANL DKKMQTPKTL TSYSTTQEHT TNLSSTRTPS TTTSL
Expression Region 24-125
Protein Description Full Length of Mature Protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Rabbit C-C motif chemokine 2(CCL2),Mammalian cell
Code CSB-MP004783RB
Size Pls inquiry other sizes
Source Mammalian cell
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence QPDAVNS PVTCCYTFTN KTISVKRLMS YRRINSTKCP KEAVIFMTKL AKGICADPKQ KWVQDAIANL DKKMQTPKTL TSYSTTQEHT TNLSSTRTPS TTTSL
Expression Region 24-125
Protein Description Full Length of Mature Protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat

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