Recombinant Rabbit Sterol 26-hydroxylase, mitochondrial(CYP27A1) ,partial

Product Type Recombinant Protein
Uniprot No. P17177
Species Oryctolagus cuniculus (Rabbit)
Gene Names CYP27A1
Protein Names Recommended name: Sterol 26-hydroxylase, mitochondrial EC= 1.14.13.15 Alternative name(s): 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase Cytochrome P-450C27/25 Cytochrome P450 27 Sterol 27-hydroxylase Vitam
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Target Details This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body, this protein is important for overall cholesterol homeostasis. Mutations in this gene cause cerebrotendinous xanthomatosis, a rare autosomal recessive lipid storage disease.
Function Catalyzes the first step in the oxidation of the side chain of sterol intermediates; the 27-hydroxylation of 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol. Has also a vitamin D3-25-hydroxylase activity.
Subcellular Location Mitochondrion membrane
Protein Families Cytochrome P450 family
Tissue Specificity Expressed in all tissues tested. Highest expression in liver and duodenum, followed by adrenal gland and lung. Low expression in kidney and spleen.
Database Links

KEGG: ocu:100348736

STRING: 9986.ENSOCUP00000002930

UniGene: Ocu.1859

Pathway PPAR signaling pathway
Cholesterol metabolism

Product Details for Different Expression Systems

Product Name Recombinant Rabbit Sterol 26-hydroxylase, mitochondrial(CYP27A1) ,partial,Yeast
Code CSB-YP006405RB
Size Pls inquiry other sizes
Source Yeast
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Rabbit Sterol 26-hydroxylase, mitochondrial(CYP27A1) ,partial,E.coli
Code CSB-EP006405RB
Size Pls inquiry other sizes
Source E.coli
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-SUMO-tagged and C-terminal Myc-tagged
N-terminal His-B2M-tagged and C-terminal Myc-tagged
N-terminal His-GST-tagged and C-terminal Myc-tagged
N-terminal His-tagged
N-terminal His-SUMO-tagged
N-terminal His-B2M-tagged
N-terminal His-GST-tagged
N-terminal GST-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Rabbit Sterol 26-hydroxylase, mitochondrial(CYP27A1) ,partial,Baculovirus
Code CSB-BP006405RB
Size Pls inquiry other sizes
Source Baculovirus
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Rabbit Sterol 26-hydroxylase, mitochondrial(CYP27A1) ,partial,Mammalian cell
Code CSB-MP006405RB
Size Pls inquiry other sizes
Source Mammalian cell
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Still Have Questions? Leave a Message or Start an on-line Chat

Most popular with customers

Newsletters

Get all the latest information on Events, Sales and Offers. Sign up for newsletter today.

Copyright © 2007-2018 www.cusabio.com CUSABIO TECHNOLOGY LLC All Rights Reserved.