Recombinant Rat Dipeptidyl peptidase 1(Ctsc)

Product Type Recombinant Protein
Uniprot No. P80067
Species Rattus norvegicus (Rat)
Gene Names Ctsc
Protein Names Recommended name: Dipeptidyl peptidase 1 EC= 3.4.14.1 Alternative name(s): Cathepsin C Cathepsin J Dipeptidyl peptidase I Short name= DPP-I Short name= DPPI Dipeptidyl transferase Cleaved into the following 3 chain
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Target Details This protein, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. Multiple transcript variants encoding different isoforms have been found for this gene.
HGNC 2528
RGD 2445
MGI 109553
Function Thiol protease. Has dipeptidylpeptidase activity. Can act as both an exopeptidase and endopeptidase (By similarity).
Subcellular Location Lysosome
Protein Families Peptidase C1 family
Tissue Specificity Broadly distributed, but higher levels found in liver, spleen, intestine, lung and kidney.
Database Links

KEGG: rno:25423

STRING: 10116.ENSRNOP00000022342

UniGene: Rn.203177

Pathway Apoptosis

Product Details for Different Expression Systems

Product Name Recombinant Rat Dipeptidyl peptidase 1(Ctsc),Yeast
Code CSB-YP006186RA
Size Pls inquiry other sizes
Source Yeast
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence DTPANC TYPDLLGTWV FQVGPRHPRS HINCSVMEPT EEKVVIHLKK LDTAYDEVGN SGYFTLIYNQ GFEIVLNDYK WFAFFKYEVK GSRAISYCHE TMTGWVHDVL GRNW
Expression Region 25-134
Protein Description Full Length of Mature Protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Rat Dipeptidyl peptidase 1(Ctsc),E.coli
Code CSB-EP006186RA
Size Pls inquiry other sizes
Source E.coli
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-SUMO-tagged and C-terminal Myc-tagged
N-terminal His-B2M-tagged and C-terminal Myc-tagged
N-terminal His-GST-tagged and C-terminal Myc-tagged
N-terminal His-tagged
N-terminal His-SUMO-tagged
N-terminal His-B2M-tagged
N-terminal His-GST-tagged
N-terminal GST-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence DTPANC TYPDLLGTWV FQVGPRHPRS HINCSVMEPT EEKVVIHLKK LDTAYDEVGN SGYFTLIYNQ GFEIVLNDYK WFAFFKYEVK GSRAISYCHE TMTGWVHDVL GRNW
Expression Region 25-134
Protein Description Full Length of Mature Protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Rat Dipeptidyl peptidase 1(Ctsc),Baculovirus
Code CSB-BP006186RA
Size Pls inquiry other sizes
Source Baculovirus
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence DTPANC TYPDLLGTWV FQVGPRHPRS HINCSVMEPT EEKVVIHLKK LDTAYDEVGN SGYFTLIYNQ GFEIVLNDYK WFAFFKYEVK GSRAISYCHE TMTGWVHDVL GRNW
Expression Region 25-134
Protein Description Full Length of Mature Protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Rat Dipeptidyl peptidase 1(Ctsc),Mammalian cell
Code CSB-MP006186RA
Size Pls inquiry other sizes
Source Mammalian cell
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence DTPANC TYPDLLGTWV FQVGPRHPRS HINCSVMEPT EEKVVIHLKK LDTAYDEVGN SGYFTLIYNQ GFEIVLNDYK WFAFFKYEVK GSRAISYCHE TMTGWVHDVL GRNW
Expression Region 25-134
Protein Description Full Length of Mature Protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat

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