E3 ubiquitin-protein ligase PDZRN3
PDZ domain-containing RING finger protein 3
Semaphorin cytoplasmic domain-associated protein 3
Short name= Protein SEMACAP3
Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
E3 ubiquitin-protein ligase. Plays an important role in regulating the surface level of MUSK on myotubes. Mediates the ubiquitination of MUSK, promoting its endocytosis and lysosomal degradation. Might contribute to terminal myogenic differentiation.