Recombinant Rat Interferon-related developmental regulator 1 (Ifrd1)

Code CSB-YP011069RA
MSDS
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Source Yeast
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Code CSB-EP011069RA
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Source E.coli
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Code CSB-EP011069RA-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP011069RA
MSDS
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Source Baculovirus
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Code CSB-MP011069RA
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Ifrd1
Uniprot No.
Alternative Names
Ifrd1; Pc4; Interferon-related developmental regulator 1; IRPR; Nerve growth factor-inducible protein PC4
Species
Rattus norvegicus (Rat)
Expression Region
1-449
Target Protein Sequence
MPKNKKRNAP HRGGGGGGGS GAATSAATTG GPHRTVQPFS DEDASIETMS HCSGYSDPSS FAEDGPEVLD EEGTQEDLEY KLKGLIDLTL DKSAKTRQAA LEGVKNALSS KVLYEFVLER RMTLTDSIER CLKKGKSDGQ RAAAALASVL CIQLGPGLES EEILKTLGPI LKKIICDGTA SIQARQTCAT CFGVCCFIAT DDITELYSTL ECLEGIFTKS YLKEKDTNVP CSTPNTVLHI SSLLAWTLLL TICPISEVKK KLELHFHKLP SLLSCDDVNM RIAAGESLAL LFELARGMES DFFYEDMDSL TQMLRALATD GNKHRAKVDK RKQRSVFRDV LRAVEERDFP TETVKFGPER MYIDSWVKKH TYDTFKEALG SGMQYHLQTN EFLRNVFELG PPVMLDAATL KTMKIPRFER HLYNSAAFKA RTKARSKCRD KRADVGEFF
Protein Length
Full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Probably participates in neurogenesis. Could play a role in regulating gene activity in the proliferative and/or differentiative pathways induced by NGF.
Gene References into Functions
  1. findings thus suggest that the stimulation of Errfi1 and Ifrd1 may be important for theca and granulosa cell differentiation and oocyte complexes expansion. PMID: 27358163
  2. PC4 is a regulator of transcription involved in tissue regeneration after ischemic stroke. PMID: 12691737
  3. PC4 acts as a coactivator of MyoD and MEF2C by removing the inhibitory effect of HDAC4, thus exerting a pivotal function during myogenesis. PMID: 15743821
Subcellular Location
Cytoplasm. Cell membrane. Nucleus. Note=Presents a NGF-dependent pattern of intracellular localization. With increasing amounts of NGF and besides being expressed in the cytoplasm, it is also localized in the plasma membrane (inner side) at the onset of NGF-induced differentiation, from where it disappears to reappear in the nuclei of differentiated cells.
Protein Families
IFRD family
Tissue Specificity
Expressed at high levels in the embryonic brain in the period related to neuroblast proliferation and differentiation.
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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