Recombinant Rat Platelet-activating factor acetylhydrolase 2, cytoplasmic(Pafah2)

Product Type Recombinant Protein
Uniprot No. P83006
Species Rattus norvegicus (Rat)
Gene Names Pafah2
Protein Names Recommended name: Platelet-activating factor acetylhydrolase 2, cytoplasmic EC= 3.1.1.47 Alternative name(s): Serine-dependent phospholipase A2 Short name= SD-PLA2
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Target Details This gene encodes platelet-activating factor acetylhydrolase isoform 2, a single-subunit intracellular enzyme that catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). However, this lipase exhibits a broader substrate specificity than simply platelet activating factor. Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist, and both are multi-subunit enzymes. Additionally, there is a single-subunit serum isoform of this enzyme.
HGNC 8579
RGD 631399
MGI 2140321
Function Has a marked selectivity for phospholipids with short acyl chains at the sn-2 position. May share a common physiologic function with the plasma-type enzyme. Catalyzes transacetylation of the acetyl group from platelet-activating factor (PAF) to lysoplasmalogen and to sphingosine, producing plasmalogen analogs of PAF and N-acetylsphingosine (C2-ceramide) respectively. Acts as a PAF-acetylhydrolase in the absence of lipid acceptor molecules.
Subcellular Location Microsome membrane, Lipid-anchor, Mitochondrion membrane, Lipid-anchor, Cytoplasm, Endoplasmic reticulum membrane, Lipid-anchor
Protein Families Serine esterase family
Tissue Specificity Expressed in kidney.
Database Links

KEGG: rno:313611

STRING: 10116.ENSRNOP00000034439

UniGene: Rn.92487

Product Details for Different Expression Systems

Product Name Recombinant Rat Platelet-activating factor acetylhydrolase 2, cytoplasmic(Pafah2),Yeast
Code CSB-YP017388RA
Size Pls inquiry other sizes
Source Yeast
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MGAGQSICFP PISGPHHIGC TDVMEGHSLE GSLFRLFYPC EASETCEQPL WIPRYEYCVG LADYLQYNKR WVGLLFNVGI GSCRLPVSWN GPFKTKESGY PLIILSHGLG GFRVSYSAFC MELASRGFVV AAIEHRDQSA AATYFCKQTS QESSPTESLE EEWIPFRRIK EGEKEFHVRN PQVHQRAKEC VRVLQILQDA SAGKPVINVF PGGLDLMTLK GSIDMSRVAV MGHSFGGATA ILALTQEAQF RCAIALDAWM FPLEHDFYPK ARGPVFFINV EKFQTVESVN LMKKICAQHE QSRIVTVLGA VHRSQTDFAF VTGNMIGKLF SSGTRGTLDP YEGQEVMVRA MLAFLQKHLD LKEDYDQWNS FIEGIGPSLI QGAPHYLSSL
Expression Region 1-390
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Rat Platelet-activating factor acetylhydrolase 2, cytoplasmic(Pafah2),E.coli
Code CSB-EP017388RA
Size Pls inquiry other sizes
Source E.coli
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-SUMO-tagged and C-terminal Myc-tagged
N-terminal His-B2M-tagged and C-terminal Myc-tagged
N-terminal His-GST-tagged and C-terminal Myc-tagged
N-terminal His-tagged
N-terminal His-SUMO-tagged
N-terminal His-B2M-tagged
N-terminal His-GST-tagged
N-terminal GST-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MGAGQSICFP PISGPHHIGC TDVMEGHSLE GSLFRLFYPC EASETCEQPL WIPRYEYCVG LADYLQYNKR WVGLLFNVGI GSCRLPVSWN GPFKTKESGY PLIILSHGLG GFRVSYSAFC MELASRGFVV AAIEHRDQSA AATYFCKQTS QESSPTESLE EEWIPFRRIK EGEKEFHVRN PQVHQRAKEC VRVLQILQDA SAGKPVINVF PGGLDLMTLK GSIDMSRVAV MGHSFGGATA ILALTQEAQF RCAIALDAWM FPLEHDFYPK ARGPVFFINV EKFQTVESVN LMKKICAQHE QSRIVTVLGA VHRSQTDFAF VTGNMIGKLF SSGTRGTLDP YEGQEVMVRA MLAFLQKHLD LKEDYDQWNS FIEGIGPSLI QGAPHYLSSL
Expression Region 1-390
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Rat Platelet-activating factor acetylhydrolase 2, cytoplasmic(Pafah2),Baculovirus
Code CSB-BP017388RA
Size Pls inquiry other sizes
Source Baculovirus
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MGAGQSICFP PISGPHHIGC TDVMEGHSLE GSLFRLFYPC EASETCEQPL WIPRYEYCVG LADYLQYNKR WVGLLFNVGI GSCRLPVSWN GPFKTKESGY PLIILSHGLG GFRVSYSAFC MELASRGFVV AAIEHRDQSA AATYFCKQTS QESSPTESLE EEWIPFRRIK EGEKEFHVRN PQVHQRAKEC VRVLQILQDA SAGKPVINVF PGGLDLMTLK GSIDMSRVAV MGHSFGGATA ILALTQEAQF RCAIALDAWM FPLEHDFYPK ARGPVFFINV EKFQTVESVN LMKKICAQHE QSRIVTVLGA VHRSQTDFAF VTGNMIGKLF SSGTRGTLDP YEGQEVMVRA MLAFLQKHLD LKEDYDQWNS FIEGIGPSLI QGAPHYLSSL
Expression Region 1-390
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Rat Platelet-activating factor acetylhydrolase 2, cytoplasmic(Pafah2),Mammalian cell
Code CSB-MP017388RA
Size Pls inquiry other sizes
Source Mammalian cell
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MGAGQSICFP PISGPHHIGC TDVMEGHSLE GSLFRLFYPC EASETCEQPL WIPRYEYCVG LADYLQYNKR WVGLLFNVGI GSCRLPVSWN GPFKTKESGY PLIILSHGLG GFRVSYSAFC MELASRGFVV AAIEHRDQSA AATYFCKQTS QESSPTESLE EEWIPFRRIK EGEKEFHVRN PQVHQRAKEC VRVLQILQDA SAGKPVINVF PGGLDLMTLK GSIDMSRVAV MGHSFGGATA ILALTQEAQF RCAIALDAWM FPLEHDFYPK ARGPVFFINV EKFQTVESVN LMKKICAQHE QSRIVTVLGA VHRSQTDFAF VTGNMIGKLF SSGTRGTLDP YEGQEVMVRA MLAFLQKHLD LKEDYDQWNS FIEGIGPSLI QGAPHYLSSL
Expression Region 1-390
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat

Most popular with customers

Newsletters

Get all the latest information on Events, Sales and Offers. Sign up for newsletter today.

Copyright © 2007-2018 www.cusabio.com CUSABIO TECHNOLOGY LLC All Rights Reserved.