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Recombinant Rat Potassium channel subfamily T member 2 (Kcnt2), partial

Recombinant Rat Potassium channel subfamily T member 2 (Kcnt2), partial

Code	CSB-YP757786RA
MSDS	MSDS
Size	Pls inquire
Source	Yeast
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Code	CSB-EP757786RA
MSDS	MSDS
Size	Pls inquire
Source	E.coli
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Code	CSB-EP757786RA-B
MSDS	MSDS
Size	Pls inquire
Source	E.coli
Conjugate	Avi-tag Biotinylated E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code	CSB-BP757786RA
MSDS	MSDS
Size	Pls inquire
Source	Baculovirus
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Code	CSB-MP757786RA
MSDS	MSDS
Size	Pls inquire
Source	Mammalian cell
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Product Details
Customer Reviews and Q&A
Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

Kcnt2

Uniprot No.

Q6UVM4

Alternative Names

Kcnt2; SlickPotassium channel subfamily T member 2; Sequence like an intermediate conductance potassium channel subunit; Sodium and chloride-activated ATP-sensitive potassium channel Slo2.1

Species

Rattus norvegicus (Rat)

Protein Length

Partial

Tag Info

Tag type will be determined during the manufacturing process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Form

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.

Buffer before Lyophilization

Tris/PBS-based buffer, 6% Trehalose, pH 8.0

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Troubleshooting and FAQs

Protein FAQs

Storage Condition

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Lead Time

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Datasheet

Please contact us to get it.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function

Outward rectifying potassium channel. Produces rapidly activating outward rectifier K(+) currents. Activated by high intracellular sodium and chloride levels. Channel activity is inhibited by ATP and by inhalation anesthetics, such as isoflurane. Inhibited upon stimulation of G-protein coupled receptors, such as CHRM1 and GRM1.

Gene References into Functions

Our data show SLICK expression is predominantly under the control of NFkappaB. Because neuronal NFkappaB activation occurs during stressful stimuli such as hypoxia and injury, our findings suggest that SLICK is a neuroprotective gene. PMID: 26100633
Cloning and regulation of slick channel activity. PMID: 14684870
we report the localization of Slick in the rat central nervous system using in situ and immunohistochemical techniques PMID: 15717307
Heteromer formation between Slick and Slack-B requires a specific epitope that is found in the N-terminal domain of Slack-B and that is absent in the Slack-A isoform. PMID: 19403831

Subcellular Location

Cell membrane; Multi-pass membrane protein.

Protein Families

Potassium channel family, Calcium-activated (TC 1.A.1.3) subfamily, KCa4.2/KCNT2 sub-subfamily

Tissue Specificity

Detected in brain, and at low levels in heart. Detected in brainstem, including auditory neurons such as the medial nucleus of the trapezoid body. Detected in the olfactory bulb, red nucleus, facial nucleus, pontine nucleus, oculomotor nucleus, substantia

Database Links

KEGG: rno:304827

UniGene: Rn.212417

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