Recombinant Rat Protein-arginine deiminase type-3(Padi3)

Product Type Recombinant Protein
Uniprot No. P70708
Species Rattus norvegicus (Rat)
Gene Names Padi3
Protein Names Recommended name: Protein-arginine deiminase type-3 EC= 3.5.3.15 Alternative name(s): Peptidylarginine deiminase III Protein-arginine deiminase type III
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Target Details This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type III enzyme modulates hair structural proteins, such as filaggrin in the hair follicle and trichohyalin in the inner root sheath, during hair follicle formation. Together with the type I enzyme, this enzyme may also play a role in terminal differentiation of the epidermis. This gene exists in a cluster with four other paralogous genes.
Function Catalyzes the deimination of arginine residues of proteins.
Subcellular Location Cytoplasm
Protein Families Protein arginine deiminase family
Tissue Specificity Epidermis and hair follicles.
Database Links

KEGG: rno:29520

STRING: 10116.ENSRNOP00000009230

UniGene: Rn.32094

Product Details for Different Expression Systems

Product Name Recombinant Rat Protein-arginine deiminase type-3(Padi3),Yeast
Code CSB-YP017378RA
Size Pls inquiry other sizes
Source Yeast
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MSLQRTVRVS LEHPTSAVCV AGVETIVDIY GSVPEGTDMF EVYGTPGVDI YVSPSMERNR ERADTRRWCF NKGLEIIVVM NSPSNDLNDS HVQIAYHSSH EHLPLAYAVL YLTCVDITLD CDMNCADRQD RSFVDKRQWM WGPDGYGAIL LVNCDRDEVS SDAQDNCDQC VRCLQDLEDM SVMVLRTQGP ESLFDDHRLI LHTSSCDAER ARVFHVCGPE DSCEAYRCVL GPDRMSYEVP RLKGYEERFY VEGLSFPDAG FPGILSFHIT LLDDSNEDYS ETPIFTDTVV FRVAPWIMTP STLPPLEVYV CQVRNNTCFV EAVEELARKA GCKLTICPQA ENRNDRWIQD EMELGYTQAP HKTLPVVFDS PRNGELQGFP YKRILGLDFG YVTREPPDSS VSGLDSFGNL EVSPPVVANG KEYPLGRILI GGNLPGSRGR RVTQVVRDFL HAQKVQPLVE LFVDWLAVGH VDEFLSFVPA PDGKGFRLLL ASPGACFRLF QEKQKWGHGR SLLFEGVIGD RRVQTISINQ VLSNQSLINF NKFAQSCIDW NREVLKRELG LGESDIIDIP QLFKSEKRKA VAFFPDLVNM LVLGKHLGIP KPFGPIINGR CCLEEKVRSL LEPLGLHCTF IDDFTPYHML HGEVHCGTNV RREPFAFKWW HMVP
Expression Region 1-664
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
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Product Name Recombinant Rat Protein-arginine deiminase type-3(Padi3),E.coli
Code CSB-EP017378RA
Size Pls inquiry other sizes
Source E.coli
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-SUMO-tagged and C-terminal Myc-tagged
N-terminal His-B2M-tagged and C-terminal Myc-tagged
N-terminal His-GST-tagged and C-terminal Myc-tagged
N-terminal His-tagged
N-terminal His-SUMO-tagged
N-terminal His-B2M-tagged
N-terminal His-GST-tagged
N-terminal GST-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MSLQRTVRVS LEHPTSAVCV AGVETIVDIY GSVPEGTDMF EVYGTPGVDI YVSPSMERNR ERADTRRWCF NKGLEIIVVM NSPSNDLNDS HVQIAYHSSH EHLPLAYAVL YLTCVDITLD CDMNCADRQD RSFVDKRQWM WGPDGYGAIL LVNCDRDEVS SDAQDNCDQC VRCLQDLEDM SVMVLRTQGP ESLFDDHRLI LHTSSCDAER ARVFHVCGPE DSCEAYRCVL GPDRMSYEVP RLKGYEERFY VEGLSFPDAG FPGILSFHIT LLDDSNEDYS ETPIFTDTVV FRVAPWIMTP STLPPLEVYV CQVRNNTCFV EAVEELARKA GCKLTICPQA ENRNDRWIQD EMELGYTQAP HKTLPVVFDS PRNGELQGFP YKRILGLDFG YVTREPPDSS VSGLDSFGNL EVSPPVVANG KEYPLGRILI GGNLPGSRGR RVTQVVRDFL HAQKVQPLVE LFVDWLAVGH VDEFLSFVPA PDGKGFRLLL ASPGACFRLF QEKQKWGHGR SLLFEGVIGD RRVQTISINQ VLSNQSLINF NKFAQSCIDW NREVLKRELG LGESDIIDIP QLFKSEKRKA VAFFPDLVNM LVLGKHLGIP KPFGPIINGR CCLEEKVRSL LEPLGLHCTF IDDFTPYHML HGEVHCGTNV RREPFAFKWW HMVP
Expression Region 1-664
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
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Product Name Recombinant Rat Protein-arginine deiminase type-3(Padi3),Baculovirus
Code CSB-BP017378RA
Size Pls inquiry other sizes
Source Baculovirus
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MSLQRTVRVS LEHPTSAVCV AGVETIVDIY GSVPEGTDMF EVYGTPGVDI YVSPSMERNR ERADTRRWCF NKGLEIIVVM NSPSNDLNDS HVQIAYHSSH EHLPLAYAVL YLTCVDITLD CDMNCADRQD RSFVDKRQWM WGPDGYGAIL LVNCDRDEVS SDAQDNCDQC VRCLQDLEDM SVMVLRTQGP ESLFDDHRLI LHTSSCDAER ARVFHVCGPE DSCEAYRCVL GPDRMSYEVP RLKGYEERFY VEGLSFPDAG FPGILSFHIT LLDDSNEDYS ETPIFTDTVV FRVAPWIMTP STLPPLEVYV CQVRNNTCFV EAVEELARKA GCKLTICPQA ENRNDRWIQD EMELGYTQAP HKTLPVVFDS PRNGELQGFP YKRILGLDFG YVTREPPDSS VSGLDSFGNL EVSPPVVANG KEYPLGRILI GGNLPGSRGR RVTQVVRDFL HAQKVQPLVE LFVDWLAVGH VDEFLSFVPA PDGKGFRLLL ASPGACFRLF QEKQKWGHGR SLLFEGVIGD RRVQTISINQ VLSNQSLINF NKFAQSCIDW NREVLKRELG LGESDIIDIP QLFKSEKRKA VAFFPDLVNM LVLGKHLGIP KPFGPIINGR CCLEEKVRSL LEPLGLHCTF IDDFTPYHML HGEVHCGTNV RREPFAFKWW HMVP
Expression Region 1-664
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Rat Protein-arginine deiminase type-3(Padi3),Mammalian cell
Code CSB-MP017378RA
Size Pls inquiry other sizes
Source Mammalian cell
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MSLQRTVRVS LEHPTSAVCV AGVETIVDIY GSVPEGTDMF EVYGTPGVDI YVSPSMERNR ERADTRRWCF NKGLEIIVVM NSPSNDLNDS HVQIAYHSSH EHLPLAYAVL YLTCVDITLD CDMNCADRQD RSFVDKRQWM WGPDGYGAIL LVNCDRDEVS SDAQDNCDQC VRCLQDLEDM SVMVLRTQGP ESLFDDHRLI LHTSSCDAER ARVFHVCGPE DSCEAYRCVL GPDRMSYEVP RLKGYEERFY VEGLSFPDAG FPGILSFHIT LLDDSNEDYS ETPIFTDTVV FRVAPWIMTP STLPPLEVYV CQVRNNTCFV EAVEELARKA GCKLTICPQA ENRNDRWIQD EMELGYTQAP HKTLPVVFDS PRNGELQGFP YKRILGLDFG YVTREPPDSS VSGLDSFGNL EVSPPVVANG KEYPLGRILI GGNLPGSRGR RVTQVVRDFL HAQKVQPLVE LFVDWLAVGH VDEFLSFVPA PDGKGFRLLL ASPGACFRLF QEKQKWGHGR SLLFEGVIGD RRVQTISINQ VLSNQSLINF NKFAQSCIDW NREVLKRELG LGESDIIDIP QLFKSEKRKA VAFFPDLVNM LVLGKHLGIP KPFGPIINGR CCLEEKVRSL LEPLGLHCTF IDDFTPYHML HGEVHCGTNV RREPFAFKWW HMVP
Expression Region 1-664
Protein Description Full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat

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