Recombinant Rat Serine/threonine-protein kinase DCLK2 (Dclk2)

Code CSB-YP702806RA
MSDS
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Source Yeast
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Code CSB-EP702806RA
MSDS
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Source E.coli
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Code CSB-EP702806RA-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP702806RA
MSDS
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Source Baculovirus
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Code CSB-MP702806RA
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Dclk2
Uniprot No.
Alternative Names
Dclk2; Dcamkl2; Dck2; Serine/threonine-protein kinase DCLK2; EC 2.7.11.1; CaMK-like CREB regulatory kinase 2; CL2; CLICK-II; CLICK2; Doublecortin-like and CAM kinase-like 2; Doublecortin-like kinase 2
Species
Rattus norvegicus (Rat)
Expression Region
1-767
Target Protein Sequence
MASTRSIELE HFEERDKRPR PGSRRGAPSS SGGSSISGPK GNGLIPSPAH SAHCSFYRTR TLQALSSEKK AKKARFYRNG DRYFKGLVFA ISSDRFRSFD ALLIELTRSL SDNVNLPQGV RTIYTVDGSR KVTSLDELLE GESYVCASNE PFRKVDYTKN VNPNWSVNIK GGTTRTLAVA SAKSEVKESK DFIKPKLVTV IRSGVKPRKA VRILLNKKTA HSFEQVLTDI TEAIKLDSGV VKRLCTLDGK QVTCLQDFFG DDDVFIACGP EKYRYAQDDF VLDHSECRVL KSSYSRASAA KYSGSRSPGL SRRSKSPASV KRAGHSSAYS TAKSPVNGTP SSQLSTPKST KSSSSSPTSP GSFRGLKQIS AQGRSSSNVN GGPELDRCMS PEGVNGNRCS ESFTLLEKYR IGKVIGDGNF AVVKECMDRS TGKEFALKII DKAKCCGKEH LIENEVSILR RVKHPNIIML VEEMETTTEL FLVMELVKGG DLFDAITSST KYTERDGSAM VYNLASALRY LHGLSIVHRD IKPENLLVCE YPDGTKSLKL GDFGLATVVE GPLYTVCGTP TYVAPEIIAE TGYGLKVDVW AAGVITYILL CGFPPFRSEN NLQEDLFDQI LAGKLEFPAP YWDNITDSAK ELISQMLQVN VEARCTAGEI LSHPWVSDDA SQENNMQAEV TGKLKQHFNN ALPKQNSTTT GVSVIMNTAL DKEGQVFCSK HCRDSSKSSR EQTSAREAPP PPESPRPPGP PATSGCDPAG TWRRHRD
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Protein kinase with a significantly reduced Ca(2+)+/CAM affinity and dependence compared to other members of the CaMK family. May play a role in the down-regulation of CRE-dependent gene activation probably by phosphorylation of the CREB coactivator CRTC2/TORC2 and the resulting retention of TORC2 in the cytoplasm.
Gene References into Functions
  1. Doublecortin kinase-2 is associated with terminal segments of axons and dendrites PMID: 15611072
Subcellular Location
Cytoplasm, cytoskeleton. Note=Colocalizes with microtubules. When overexpressed in sympathetic neurons, localizes to cell body and to the terminal segments of axons and dendrites.
Protein Families
Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily
Database Links
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Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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