Recombinant Streptococcus pyogenes serotype M4 Serine hydroxymethyltransferase(glyA)

Product Type Recombinant Protein
Uniprot No. Q1J6L7
Abbreviation glyA
Species Streptococcus pyogenes serotype M4 (strain MGAS10750)
Gene Names glyA
Protein Names Recommended name: Serine hydroxymethyltransferase Short name= SHMT Short name= Serine methylase EC= 2.1.2.1
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Function Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
Subcellular Location Cytoplasm
Protein Families SHMT family
Database Links

KEGG: spi:MGAS10750_Spy1016

Product Details for Different Expression Systems

Product Name Recombinant Streptococcus pyogenes serotype M4 Serine hydroxymethyltransferase(glyA),Yeast
Code CSB-YP629131SAAW
Size Pls inquiry other sizes
Source Yeast
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MTMIFDKGNV EDFDKELWDA IHAEEERQEH HIELIASENM VSKAVMAAQG SVLTNKYAES YPGNRYYGGT ECVDIVETLA IERAKKLFGA AFANVQAHSG SQANAAAYMA LIEAGDTVLG MDLAAGGHLT HGSPVNFSGK TYHFVGYSVD ADTETLNYEA ILEQAKAVQP KLIVAGASAY SRSIDFEKFR AIADHVGAYL MVDMAHIAGL VAAGVHPSPV PYAHIVTSTT HKTLRGPRGG LILTNDEALA KKINSAVFPG LQGGPLEHVI AAKAVAFKEA LDPAFKDYAQ AIIDNTAAMA AVFAQDDRFR LISGGTDNHV FLVDVTKVIA NGKLAQNLLD EVNITLNKNA IPFETLSPFK TSGIRIGCAA ITSRGMSVKE SQTIARLIIK ALVNHDQETI LEEVRQEVRQ LTDAFPLYKK
Expression Region 1-420
Protein Description full length protein
Storage Buffer Tris-based buffer,50% glycerol
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Product Name Recombinant Streptococcus pyogenes serotype M4 Serine hydroxymethyltransferase(glyA),E.coli
Code CSB-EP629131SAAW
Size Pls inquiry other sizes
Source E.coli
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-SUMO-tagged and C-terminal Myc-tagged
N-terminal His-B2M-tagged and C-terminal Myc-tagged
N-terminal His-GST-tagged and C-terminal Myc-tagged
N-terminal His-tagged
N-terminal His-SUMO-tagged
N-terminal His-B2M-tagged
N-terminal His-GST-tagged
N-terminal GST-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MTMIFDKGNV EDFDKELWDA IHAEEERQEH HIELIASENM VSKAVMAAQG SVLTNKYAES YPGNRYYGGT ECVDIVETLA IERAKKLFGA AFANVQAHSG SQANAAAYMA LIEAGDTVLG MDLAAGGHLT HGSPVNFSGK TYHFVGYSVD ADTETLNYEA ILEQAKAVQP KLIVAGASAY SRSIDFEKFR AIADHVGAYL MVDMAHIAGL VAAGVHPSPV PYAHIVTSTT HKTLRGPRGG LILTNDEALA KKINSAVFPG LQGGPLEHVI AAKAVAFKEA LDPAFKDYAQ AIIDNTAAMA AVFAQDDRFR LISGGTDNHV FLVDVTKVIA NGKLAQNLLD EVNITLNKNA IPFETLSPFK TSGIRIGCAA ITSRGMSVKE SQTIARLIIK ALVNHDQETI LEEVRQEVRQ LTDAFPLYKK
Expression Region 1-420
Protein Description full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Streptococcus pyogenes serotype M4 Serine hydroxymethyltransferase(glyA),Baculovirus
Code CSB-BP629131SAAW
Size Pls inquiry other sizes
Source Baculovirus
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MTMIFDKGNV EDFDKELWDA IHAEEERQEH HIELIASENM VSKAVMAAQG SVLTNKYAES YPGNRYYGGT ECVDIVETLA IERAKKLFGA AFANVQAHSG SQANAAAYMA LIEAGDTVLG MDLAAGGHLT HGSPVNFSGK TYHFVGYSVD ADTETLNYEA ILEQAKAVQP KLIVAGASAY SRSIDFEKFR AIADHVGAYL MVDMAHIAGL VAAGVHPSPV PYAHIVTSTT HKTLRGPRGG LILTNDEALA KKINSAVFPG LQGGPLEHVI AAKAVAFKEA LDPAFKDYAQ AIIDNTAAMA AVFAQDDRFR LISGGTDNHV FLVDVTKVIA NGKLAQNLLD EVNITLNKNA IPFETLSPFK TSGIRIGCAA ITSRGMSVKE SQTIARLIIK ALVNHDQETI LEEVRQEVRQ LTDAFPLYKK
Expression Region 1-420
Protein Description full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Streptococcus pyogenes serotype M4 Serine hydroxymethyltransferase(glyA),Mammalian cell
Code CSB-MP629131SAAW
Size Pls inquiry other sizes
Source Mammalian cell
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MTMIFDKGNV EDFDKELWDA IHAEEERQEH HIELIASENM VSKAVMAAQG SVLTNKYAES YPGNRYYGGT ECVDIVETLA IERAKKLFGA AFANVQAHSG SQANAAAYMA LIEAGDTVLG MDLAAGGHLT HGSPVNFSGK TYHFVGYSVD ADTETLNYEA ILEQAKAVQP KLIVAGASAY SRSIDFEKFR AIADHVGAYL MVDMAHIAGL VAAGVHPSPV PYAHIVTSTT HKTLRGPRGG LILTNDEALA KKINSAVFPG LQGGPLEHVI AAKAVAFKEA LDPAFKDYAQ AIIDNTAAMA AVFAQDDRFR LISGGTDNHV FLVDVTKVIA NGKLAQNLLD EVNITLNKNA IPFETLSPFK TSGIRIGCAA ITSRGMSVKE SQTIARLIIK ALVNHDQETI LEEVRQEVRQ LTDAFPLYKK
Expression Region 1-420
Protein Description full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat

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