Recombinant Varicella-zoster virus Tegument protein 7 (ORF7)

Code CSB-YP678309VAQ
MSDS
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Source Yeast
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Code CSB-EP678309VAQ
MSDS
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Source E.coli
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Code CSB-EP678309VAQ-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP678309VAQ
MSDS
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Source Baculovirus
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Code CSB-MP678309VAQ
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
ORF7
Uniprot No.
Alternative Names
ORF7; Tegument protein UL51 homolog; Protein ORF7
Species
Varicella-zoster virus (strain Oka vaccine) (HHV-3) (Human herpesvirus 3)
Expression Region
1-259
Target Protein Sequence
MQTVCASLCG YARIPTEEPS YEEVRVNTHP QGAALLRLQE ALTAVNGLLP APLTLEDVVA SADNTRRLVR AQALARTYAA CSRNIECLKQ HHFTEDNPGL NAVVRSHMEN SKRLADMCLA AITHLYLSVG AVDVTTDDIV DQTLRMTAES EVVMSDVVLL EKTLGVVAKP QASFDVSHNH ELSIAKGENV GLKTSPIKSE ATQLSEIKPP LIEVSDNNTS NLTKKTYPTE TLQPVLTPKQ TQDVQRTTPA IKKSHVMLV
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Plays several roles during the time course of infection, including egress of virus particles from the perinuclear space and secondary envelopment of cytoplasmic capsids that bud into specific trans-Golgi network (TGN)-derived membranes. Localizes its binding partner ORF53 to the host trans-Golgi network (TGN).
Gene References into Functions
  1. study found that ORF7 is required for VZV cytoplasmic envelopment in differentiated neuronal cells, and the envelopment deficiency caused by ORF7 deletion results in poor dissemination of VZV among neuronal cells; findings imply that ORF7 plays a role in neuropathy PMID: 28356523
  2. Interestingly, ORF7 deletion completely abolishes viral spread in human nervous tissue ex vivo and in an in vivo mouse model. PMID: 22674980
  3. One of the genes (ORF7) has never been described as a skin tropic factor. PMID: 20617166
Subcellular Location
Virion. Virion tegument. Host cytoplasm. Host Golgi apparatus.
Protein Families
Herpesviridae UL51 family
Database Links

KEGG: vg:1487677

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