Recombinant Xenopus laevis ELAV-like protein 4 (elavl4)

Code CSB-YP763069XBE
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Source Yeast
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Code CSB-EP763069XBE
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Source E.coli
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Code CSB-EP763069XBE-B
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP763069XBE
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Source Baculovirus
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Code CSB-MP763069XBE
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
elavl4
Uniprot No.
Alternative Names
elavl4; elrDELAV-like protein 4; Protein ElrD
Species
Xenopus laevis (African clawed frog)
Expression Region
1-400
Target Protein Sequence
MEWNGLKMII STMEPQVSNG PTSNTSNGPS SNSRNCPSPM QTGAATDDSK TNLIVNYLPQ NMTQEEFRSL FGSIGEIESC KLVRDKITGT QFEENFKDLA TGTKWKPLTE EGPIFGKGQS LGYGFVNYID PKDAEKAINT LNGLRLQTKT IKVSYARPSS ASIRDANLYV SGLPKTMTQK ELEQLFSQYG RIITSRILVD QVTGVSRGVG FIRFDKRIEA EEAIKGLNGQ KPSGAAEPIT VKFANNPSQK TSQALLSQLY QSPNRRYPGP LHHQAQRFRL DNLLNMAYGV KRFSPITIDG MTSLVGMNIP GHTGTGWCIF VYNLSPDSDE SVLWQLFGPF GAVNNVKVIR DFNTNKCKGF GFVTMTNYDE AAMAIASLNG YRLGDRVLQV SFKTNKTHKS
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
RNA-binding protein that is involved in the post-transcriptional regulation of mRNAs. Plays a role in the regulation of mRNA stability, alternative splicing and translation. Binds to AU-rich element (ARE) sequences in the 3' untranslated region (3'UTR) of target mRNAs. Mainly play a role in neuron-specific RNA processing.
Gene References into Functions
  1. Data show that the two elrD transcripts, elrD1 and elrD2, present the same tissue-specific pattern of expression, with distinct developmental regulation. PMID: 21425088
  2. elrD expression was detected in developing Xenopus retina from stage 26 onwards in the differentiating ganglion cell layer. PMID: 15593335
Subcellular Location
Cytoplasm. Perikaryon. Cell projection, axon. Cell projection, dendrite. Cell projection, growth cone.
Protein Families
RRM elav family
Tissue Specificity
Expression is neural-specific. In the retina, expressed in the ganglion cell layer from stage 28 onwards and in amacrine cells from stage 35 onwards. Expressed in the tailbud and adult brain; in tailbuds, expression is predominant in the cortical plate.
Database Links

KEGG: xla:386602

UniGene: Xl.1036

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