Recombinant Xenopus laevis Noggin(nog)

Product Type Recombinant Protein
Uniprot No. P49011
Species Xenopus laevis (African clawed frog)
Gene Names nog
Protein Names Recommended name: Noggin
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Function Patterns the embryo by interrupting bone morphogenetic proteins (BMP) signaling. Binds BMP-4 and BMP-2 with high affinity. Can abolish BMP-4 activity by blocking binding to cognate cell-surface receptors. Capable of inducing dorsal development in embryos. Causes dorsal mesodermal differentiation of animal cap ectoderm when coexpressed with xWNT-8 and nuclear, sequence-specific DNA-binding protein xBRA. None of these molecules causes dorsal mesoderm formation when expressed alone.
Subcellular Location Secreted
Protein Families Noggin family
Database Links

KEGG: xla:373646

UniGene: Xl.834

Pathway TGF-beta signaling pathway

Product Details for Different Expression Systems

Product Name Recombinant Xenopus laevis Noggin(nog),Yeast
Code CSB-YP015917XBE
Size Pls inquiry other sizes
Source Yeast
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence R IDQGGCQHYL HIRPAPSENL PLVDLIEHPD PIYDPKEKDL NETLLRTLMV GHFDPNFMAT ILPEERLGVE DLGELDLLLR QKPSGAMPAE IKGLEFYEGL QSKKHRLSKK LRRKLQMWLW SQTFCPVLYT WNDLGTRFWP RYVKVGSCYS KRSCSVPEGM VCKAAKSMHL TILRWRCQRR VQQKCAWITI QYPVISECKC SC
Expression Region 20-222
Protein Description Full Length of Mature Protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Xenopus laevis Noggin(nog),E.coli
Code CSB-EP015917XBE
Size Pls inquiry other sizes
Source E.coli
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-SUMO-tagged and C-terminal Myc-tagged
N-terminal His-B2M-tagged and C-terminal Myc-tagged
N-terminal His-GST-tagged and C-terminal Myc-tagged
N-terminal His-tagged
N-terminal His-SUMO-tagged
N-terminal His-B2M-tagged
N-terminal His-GST-tagged
N-terminal GST-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence R IDQGGCQHYL HIRPAPSENL PLVDLIEHPD PIYDPKEKDL NETLLRTLMV GHFDPNFMAT ILPEERLGVE DLGELDLLLR QKPSGAMPAE IKGLEFYEGL QSKKHRLSKK LRRKLQMWLW SQTFCPVLYT WNDLGTRFWP RYVKVGSCYS KRSCSVPEGM VCKAAKSMHL TILRWRCQRR VQQKCAWITI QYPVISECKC SC
Expression Region 20-222
Protein Description Full Length of Mature Protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Xenopus laevis Noggin(nog),Baculovirus
Code CSB-BP015917XBE
Size Pls inquiry other sizes
Source Baculovirus
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence R IDQGGCQHYL HIRPAPSENL PLVDLIEHPD PIYDPKEKDL NETLLRTLMV GHFDPNFMAT ILPEERLGVE DLGELDLLLR QKPSGAMPAE IKGLEFYEGL QSKKHRLSKK LRRKLQMWLW SQTFCPVLYT WNDLGTRFWP RYVKVGSCYS KRSCSVPEGM VCKAAKSMHL TILRWRCQRR VQQKCAWITI QYPVISECKC SC
Expression Region 20-222
Protein Description Full Length of Mature Protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Xenopus laevis Noggin(nog),Mammalian cell
Code CSB-MP015917XBE
Size Pls inquiry other sizes
Source Mammalian cell
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence R IDQGGCQHYL HIRPAPSENL PLVDLIEHPD PIYDPKEKDL NETLLRTLMV GHFDPNFMAT ILPEERLGVE DLGELDLLLR QKPSGAMPAE IKGLEFYEGL QSKKHRLSKK LRRKLQMWLW SQTFCPVLYT WNDLGTRFWP RYVKVGSCYS KRSCSVPEGM VCKAAKSMHL TILRWRCQRR VQQKCAWITI QYPVISECKC SC
Expression Region 20-222
Protein Description Full Length of Mature Protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat

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