Recombinant Xenopus tropicalis Iroquois-class homeodomain protein irx-3(irx3)

Product Type Recombinant Protein
Uniprot No. Q6NVN3
Abbreviation irx3
Species Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Gene Names irx3
Protein Names Recommended name: Iroquois-class homeodomain protein irx-3 Alternative name(s): Iroquois homeobox protein 3
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Function Acts partially redundantly with other irx members in neural patterning. Required for formation of the posterior forebrain, midbrain, hindbrain, and to a lesser extent, spinal cord. Both up-regulates and down-regulates gene expression during neural development. Acts early in neural plate development to induce proneural gene expression and specify a neural precursor state. Also up-regulates repressors that prevent neuronal differentiation. Required during at least two stages of pronephros kidney development; during neurula stages, maintains transcription of key renal genes to define the size and identity of the pronephric anlage, probably in part through regulation of bmp-signaling. Subsequently required for proper formation of the intermediate tubule segment of the pronephros.
Subcellular Location Nucleus
Protein Families TALE/IRO homeobox family
Tissue Specificity Expressed in the neural plate in overlapping patterns with other irx members, which all share an anterior border of expression. Outside the nervous system and at tailbud stages, expressed in the developing otic vesicle, branchial arches, prospective heart
Database Links

KEGG: xtr:407888

STRING: 8364.ENSXETP00000012797

UniGene: Str.51982

Product Details for Different Expression Systems

Product Name Recombinant Xenopus tropicalis Iroquois-class homeodomain protein irx-3(irx3),Yeast
Code CSB-YP744000XBF
Size Pls inquiry other sizes
Source Yeast
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MSFPQLGYQY IRPLYPSDRQ NVGGTRSGTE LSPAGTLSNV LSSVYGTPYA AAAAAQAYGA FLPYSAELPI FPQLGSQYEM KDSPGVQHAA FSHPHAAFYP YGQYQFGDPS RPKNATREST STLKAWLNEH RKNPYPTKGE KIMLAIITKM TLTQVSTWFA NARRRLKKEN KMTWAPRSRT DEEGNAYGSD HEEDKHEDDE EIDLENIDTE DIESKEDLDD PDTDIHSDSK TDARSDSEAS DGFEDLNAPE DRLLKSVVGQ RQVLNEEPQD KCALSSDAKA SQPACEQIKL DRIPSSPPLE NNIPAAHKPK IWSLAETATT PDNPRRSPNT GGSVNTQNLI AQHRLIASPG SRFQGWTGRA FSAQQLSLLN SAHFLQGLSV SHTALGSGTA SFPKAAEPKH STDSLTDRSS TVDIEKKIPV LNTAFQPVQR RSQNQLDAAM ILSALSSS
Expression Region 1-448
Protein Description full length protein
Storage Buffer Tris-based buffer,50% glycerol
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Product Name Recombinant Xenopus tropicalis Iroquois-class homeodomain protein irx-3(irx3),E.coli
Code CSB-EP744000XBF
Size Pls inquiry other sizes
Source E.coli
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-SUMO-tagged and C-terminal Myc-tagged
N-terminal His-B2M-tagged and C-terminal Myc-tagged
N-terminal His-GST-tagged and C-terminal Myc-tagged
N-terminal His-tagged
N-terminal His-SUMO-tagged
N-terminal His-B2M-tagged
N-terminal His-GST-tagged
N-terminal GST-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MSFPQLGYQY IRPLYPSDRQ NVGGTRSGTE LSPAGTLSNV LSSVYGTPYA AAAAAQAYGA FLPYSAELPI FPQLGSQYEM KDSPGVQHAA FSHPHAAFYP YGQYQFGDPS RPKNATREST STLKAWLNEH RKNPYPTKGE KIMLAIITKM TLTQVSTWFA NARRRLKKEN KMTWAPRSRT DEEGNAYGSD HEEDKHEDDE EIDLENIDTE DIESKEDLDD PDTDIHSDSK TDARSDSEAS DGFEDLNAPE DRLLKSVVGQ RQVLNEEPQD KCALSSDAKA SQPACEQIKL DRIPSSPPLE NNIPAAHKPK IWSLAETATT PDNPRRSPNT GGSVNTQNLI AQHRLIASPG SRFQGWTGRA FSAQQLSLLN SAHFLQGLSV SHTALGSGTA SFPKAAEPKH STDSLTDRSS TVDIEKKIPV LNTAFQPVQR RSQNQLDAAM ILSALSSS
Expression Region 1-448
Protein Description full length protein
Storage Buffer Tris-based buffer,50% glycerol
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Product Name Recombinant Xenopus tropicalis Iroquois-class homeodomain protein irx-3(irx3),Baculovirus
Code CSB-BP744000XBF
Size Pls inquiry other sizes
Source Baculovirus
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MSFPQLGYQY IRPLYPSDRQ NVGGTRSGTE LSPAGTLSNV LSSVYGTPYA AAAAAQAYGA FLPYSAELPI FPQLGSQYEM KDSPGVQHAA FSHPHAAFYP YGQYQFGDPS RPKNATREST STLKAWLNEH RKNPYPTKGE KIMLAIITKM TLTQVSTWFA NARRRLKKEN KMTWAPRSRT DEEGNAYGSD HEEDKHEDDE EIDLENIDTE DIESKEDLDD PDTDIHSDSK TDARSDSEAS DGFEDLNAPE DRLLKSVVGQ RQVLNEEPQD KCALSSDAKA SQPACEQIKL DRIPSSPPLE NNIPAAHKPK IWSLAETATT PDNPRRSPNT GGSVNTQNLI AQHRLIASPG SRFQGWTGRA FSAQQLSLLN SAHFLQGLSV SHTALGSGTA SFPKAAEPKH STDSLTDRSS TVDIEKKIPV LNTAFQPVQR RSQNQLDAAM ILSALSSS
Expression Region 1-448
Protein Description full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Xenopus tropicalis Iroquois-class homeodomain protein irx-3(irx3),Mammalian cell
Code CSB-MP744000XBF
Size Pls inquiry other sizes
Source Mammalian cell
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MSFPQLGYQY IRPLYPSDRQ NVGGTRSGTE LSPAGTLSNV LSSVYGTPYA AAAAAQAYGA FLPYSAELPI FPQLGSQYEM KDSPGVQHAA FSHPHAAFYP YGQYQFGDPS RPKNATREST STLKAWLNEH RKNPYPTKGE KIMLAIITKM TLTQVSTWFA NARRRLKKEN KMTWAPRSRT DEEGNAYGSD HEEDKHEDDE EIDLENIDTE DIESKEDLDD PDTDIHSDSK TDARSDSEAS DGFEDLNAPE DRLLKSVVGQ RQVLNEEPQD KCALSSDAKA SQPACEQIKL DRIPSSPPLE NNIPAAHKPK IWSLAETATT PDNPRRSPNT GGSVNTQNLI AQHRLIASPG SRFQGWTGRA FSAQQLSLLN SAHFLQGLSV SHTALGSGTA SFPKAAEPKH STDSLTDRSS TVDIEKKIPV LNTAFQPVQR RSQNQLDAAM ILSALSSS
Expression Region 1-448
Protein Description full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat

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