Recombinant Bovine Desmocollin-2(DSC2)

Code CSB-CF007190BO
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. P33545
Storage Buffer Tris-based buffer,50% glycerol
Species Bos taurus (Bovine)
Sequence RWAPIPCSVPENSLGPFPLFLQQIQSDTAQNYTIYYSISGPGVDKEPRNLFYVERDTGNLFCTASIDRETYPLFELVAFATTPDGYTPEYPLTLVIRIEDENDNAPIFTETSYSFEVFENSKVGTTVGQVCATDQDEPDTLHTRLKYSIIEQFPALPTLFSMHPTTGVITTSSSKLDRELIDKYQLKIKVQDMDGQYFGLQTTAICIINIEDVNDNLPTFTRSSYVASVEENRIDVEILRVAVRDKDLINTANWRANYTILKGNEDGNFKIVTDSQTNEGVLCVVKPLNYEEKQQVTLEIGVVNEAPYTGTSRSTTNMATVTVNVQNQDEGPECDPRVQTVRIKENVPVGTKTIGYKAYDPETGSSSGIRYKKSSDPEGWVDVDKNSGVITILKRLDREARSGVYNISIIASDKDGRTCNGVLGIVLEDVNDNGPVIPQRTVVICKTVMSSAEIVAVDPDEPIHGPPFDFSLEGVSDSEVLRMWRLTKVNDTAARLSYLNDLRFGKYTVPVRVTDRLGQSLVTQLVVILCDCVTPNDCSFRPVSRTGNREVILGKWAILAILLGIALLFCILFTLVCGATTGADKKPKVFPDDLAQQNLIVSNTEAPGDDKVYSTNDFTTHAVGGSAHGIGGTLGSRVKNGGQETIEMVKGGHQTMESCQETGHDHTLERCKEGGQHTLDSCRGGPVATDNCKYTYSEWYTYTQPRLGEKVQQCDQDNTHMQAQDYVLTYNYEGRGSAAGSVGCCSERQEEDGLEFLDHLGPKFRTLAETCMKR
Source in vitro E.coli expression system
Gene Names DSC2
Protein Names Recommended name: Desmocollin-2 Alternative name(s): Epithelial type 2 desmocollin
Expression Region 90-863
Tag Info N-terminal 10xHis-tagged
Protein Description Full Length of Mature Protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms.
Subcellular Location Cell membrane, Single-pass type I membrane protein, Cell junction, desmosome
Tissue Specificity Esophagus and rumen. Weakly in epithelia and cardiac muscle.
Database Links

STRING: 9913.ENSBTAP00000011306

UniGene: Bt.4107

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