Recombinant Bovine Ectonucleoside triphosphate diphosphohydrolase 8(ENTPD8)

Code CSB-CF007697BO
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. A0JND9
Storage Buffer Tris-based buffer,50% glycerol
Species Bos taurus (Bovine)
Sequence MGLTWKQRVFTALLGAAAVSGLTALLLVLVGTMNVLLPPDTKFGIVFDAGSSHTSLFVYQWPANKENDTGIVSQALACQAEGPGISSYASNPARVGESLQGCLEEALALIPKAKHHETPMFLGATAGMRLLSRKNRSQAEDVFAAVSRALGQSPVDFRGAELLTGQDEGAFGWITINYILGLLVKYSFSGEWIRPLEETLVGALDMGGASTQITFVPGGPILDKTAQATFRLYGADHTVYTHSYLCFGRDQALSRVLAELVQASTGLLIRHPCYHSGYRGTLALASLYESPCAPAAPPDLSQNLTVEGTGNPGACVEALRKLFNFSSCDGREDCAFAGVYQPPVQGQFYAFSNFYYTFNFLNLTSKPSLSGANATIWEFCLRPWKLVEASAPPGQDRWLRDYCASGLYILTLLVEGYGFSEETWGGIEFRQQAGGADIGWTLGYMLNLTNLIPAEAPAQGWAQSFGVWAAGVVFVVLTLAATLGAVAVQVFWLQD
Source in vitro E.coli expression system
Gene Names ENTPD8
Protein Names Recommended name: Ectonucleoside triphosphate diphosphohydrolase 8 Short name= E-NTPDase 8 Short name= NTPDase 8 Short name= NTPDase8 EC= 3.6.1.5
Expression Region 1-495
Tag Info N-terminal 10xHis-tagged
Protein Description full length protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Canalicular ectonucleoside NTPDase responsible for the main hepatic NTPDase activity. Ectonucleoside NTPDases catalyze the hydrolysis of gamma- and beta-phosphate residues of nucleotides, playing a central role in concentration of extracellular nucleotides. Has activity toward ATP, ADP, UTP and UDP, but not toward AMP (By similarity).
Subcellular Location Cell membrane, Multi-pass membrane protein
Protein Families GDA1/CD39 NTPase family
Database Links

KEGG: bta:515532

STRING: 9913.ENSBTAP00000016080

UniGene: Bt.42111

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