Recombinant Bovine Ectonucleotide pyrophosphatase/phosphodiesterase family member 4(ENPP4)

Code CSB-CF007682BO
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. A2VDP5
Storage Buffer Tris-based buffer,50% glycerol
Species Bos taurus (Bovine)
Sequence NSSSASPPKLLLVSFDGFRADYLQNYEFPHLQNFIKEGVLVEQVKNVFITKTFPNHYSIVTGLYEESHGIVANSMYDVNTKKHFSDHNDKDPFWWNEAVPIWVTNQLQDNRSSAAAMWPGTDVPIHNSTPSYFMNYSPSVSFRERLGNVTTWLSSSNPPVTFATLYWEEPDASGHKYGPEDKENMRRVLEEIDEHIGELVHRLKVLGLWESLNVIITSDHGMTQCSKDRVINLDGCLDPSYYTLIDLTPVAAILPKINKTKVYSKLKVCDPHMNVYLKEDIPARFHYQHSDRIQPIILVADEGWTIVLNKSSLKLGDHGYDNSLPSMNPFLAAHGPAFHKGYKHSSINTVDIYPMMCHILGLKPHPNNGTFGHTKCLLVDQWCINLPEAIGIVIGALLVLTTLTCLIIIMQNRVSGPRPFSRLQLQEDDDDPLIG
Source in vitro E.coli expression system
Gene Names ENPP4
Protein Names Recommended name: Ectonucleotide pyrophosphatase/phosphodiesterase family member 4 Short name= E-NPP 4 Short name= NPP-4 EC= 3.1.-.-
Expression Region 19-453
Tag Info N-terminal 10xHis-tagged
Protein Description Full Length of Mature Protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors (By similarity).
Subcellular Location Cell membrane, Single-pass type I membrane protein
Protein Families Nucleotide pyrophosphatase/phosphodiesterase family
Database Links

KEGG: bta:538583

STRING: 9913.ENSBTAP00000004547

UniGene: Bt.39526

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