Recombinant Bovine Presenilins-associated rhomboid-like protein, mitochondrial(PARL)

Code CSB-CF644410BO
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. Q2KHV4
Storage Buffer Tris-based buffer,50% glycerol
Species Bos taurus (Bovine)
Source in vitro E.coli expression system
Gene Names PARL
Protein Names Recommended name: Presenilins-associated rhomboid-like protein, mitochondrial EC= Alternative name(s): Mitochondrial intramembrane cleaving protease PARL Cleaved into the following chain: 1. P-beta Short name= 2. Pbeta
Expression Region 53-377
Tag Info N-terminal 10xHis-tagged
Protein Description Full Length of Mature Protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Required for the control of apoptosis during postnatal growth. Essential for proteolytic processing of an antiapoptotic form of OPA1 which prevents the release of mitochondrial cytochrome c in response to intrinsic apoptoptic signals (By similarity).
Subcellular Location Mitochondrion inner membrane, Multi-pass membrane protein, SUBCELLULAR LOCATION: P-beta: Nucleus
Protein Families Peptidase S54 family
Database Links

KEGG: bta:514191

STRING: 9913.ENSBTAP00000019227

UniGene: Bt.4331

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