Recombinant Bovine Seipin (BSCL2)

Code CSB-CF691627BO
Size Pls inquire
Source in vitro E.coli expression system
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Product Details

Target Names
BSCL2
Uniprot No.
Alternative Names
BSCL2; Seipin; Bernardinelli-Seip congenital lipodystrophy type 2 protein homolog
Species
Bos taurus (Bovine)
Expression Region
1-394
Target Protein Sequence
MVNDPPVPALLWAQEMGHVMAGRARKLLLQFGVFFCTILLLLWVSVFLYGSFYYSYMPTV SHLSPVHFHYRTDCESSTSLLCSFPVANVTLAKGGRDRVLMYGQPYRVTLELELPESPVN QDLGMFLVTISCYTRGGRIISTSSRSVMLHYRSSLLQMLDTLVFSSLLLFGFAEQKQLLE VELYPEYRENSYVPTTGAIIEIHSKRIQMYGAYLRIHAHFTGLRYLLYNFPMTCAFVGVA SNFTFLSVIVLFSYMQWVWGGIWPRQRLSLQVNIRNRKRSRKDIQRKVSAHQPGPQGQEE SPQLSPVTEDGESHADPSGTEGQLSEEEKTEQQPLSGEEELEPEASDGSGSWEDAALLTE ANLAASGSAPAPETVGSSEPSAGSVRQRPICSSS
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

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Target Background

Function
Plays a crucial role in the formation of lipid droplets (LDs) which are storage organelles at the center of lipid and energy homeostasis. In association with LDAF1, defines the sites of LD formation in the ER. Also required for growth and maturation of small nascent LDs into larger mature LDs. Mediates the formation and/or stabilization of endoplasmic reticulum-lipid droplets (ER-LD) contacts, facilitating protein and lipid delivery from the ER into growing LDs. Regulates the maturation of ZFYVE1-positive nascent LDs and the function of the RAB18-ZFYVE1 complex in mediating the formation of ER-LD contacts. Binds anionic phospholipids including phosphatidic acid. Plays an important role in the differentiation and development of adipocytes.
Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein. Lipid droplet.
Protein Families
Seipin family
Database Links
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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