Recombinant Canine coronavirus Envelope small membrane protein(E)

Code CSB-CF339718CCO
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. P36696
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Species Canine coronavirus (strain Insavc-1) (CCoV) (Canine enteric coronavirus)
Sequence MTFPRALTVIDDNGMVISIIFWFLLIIILILFSIALLNIIKLCMVCCNLGRTVIIVPARH AYDAYKNFMQIRAYNPDEALLV
Source in vitro E.coli expression system
Gene Names E
Protein Names Recommended name: Envelope small membrane protein Short name= E protein Short name= sM protein
Expression Region 1-82
Tag Info N-terminal 10xHis-tagged
Protein Description full length protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Component of the viral envelope that plays a central role in virus morphogenesis and assembly. It is sufficient to form virus-like particles. Seems to be important for creating the membrane curvature needed to acquire the rounded, stable and infectious particle phenotype. Acts as a viroporin, inducing the formation of hydrophilic pores in cellular membranes. Also induces apoptosis (By similarity).
Subcellular Location Virion membrane, Single-pass type III membrane protein, Host Golgi apparatus membrane, Single-pass type III membrane protein
Protein Families Alphacoronaviruses E protein family

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