Recombinant Human HERV-K_1q23.3 provirus ancestral Env polyprotein

Code CSB-CF523628HU
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. O42043
Storage Buffer Tris-based buffer,50% glycerol
Species Homo sapiens (Human)
Sequence FIFTLIAVIMGLIAVTATAAVAGVALHSSVQSVNFVNYWQKNSTRLWNSQSSIDQKLASQ INDLRQTVIWMGDRLMTLEHHFQLQCDWNTSDFCITPQIYNESEHHWDMVRRHLQGREDN LTLDISKLKEQIFEASKAHLNLVPGTEAIAGVADGLANLNPVTWIKTIRSTMIINLILIV VCLFCLLLVCRCTQQLRRDSDIENGP
Source in vitro E.coli expression system
Gene Names ERVK-18
Protein Names Recommended name: HERV-K_1q23.3 provirus ancestral Env polyprotein Alternative name(s): Envelope polyprotein HERV-K(C1a) envelope protein HERV-K110 envelope protein HERV-K18 envelope protein HERV-K18 superantigen IDDMK1,2 22 en
Expression Region 355-560
Tag Info N-terminal 10xHis-tagged
Protein Description Full Length of Mature Protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This envelope protein has superantigenic properties.; FUNCTION
Subcellular Location Transmembrane protein: Cell membrane, Single-pass type I membrane protein, SUBCELLULAR LOCATION: Surface protein: Cell membrane, Peripheral membrane protein
Protein Families Beta type-B retroviral envelope protein family, HERV class-II K(HML-2) env subfamily
Tissue Specificity Expressed at higher level in the thymus. Expressed at lower level in peripheral blood lymphocytes.
Database Links

HGNC: 39025

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