Recombinant Mouse Dual oxidase maturation factor 1 (Duoxa1)

Code CSB-CF007230MO
MSDS
Size Pls inquire
Source in vitro E.coli expression system
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Product Details

Target Names
Duoxa1
Uniprot No.
Alternative Names
Duoxa1; Dual oxidase maturation factor 1; Dual oxidase activator 1
Species
Mus musculus (Mouse)
Expression Region
1-341
Target Protein Sequence
MAALGHTLPFYTGTKPTFPMDTTLAVIITIFLTALVTFIIILPGIRGKTRLFWLLRVVTS LFIGAVILAVNFSSEWSVGHVNANTTYKAFSPKWVSVDVGLQIGLGGVNITLTGTPVQQL NETINYNEAFAWRLGRSYAEEYAKALEKGLPDPVLYLAEKFTPRSPCGLYNQYRLAGHYA SAMLWVAFLCWLLANVMLSMPVLVYGGHMLLATGLFQLLALFFFSMTTSLISPCPLRLGT AVLHTHHGPAFWITLATGLLCILLGLVMAVAHRMQPHRLKAFFNQSSEDPVLEWGSEEGG LLSPHYRSIAESPETQDIPMSVASSETCFKEEHPKESDCSL
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
May be required for the maturation and the transport from the endoplasmic reticulum to the plasma membrane of functional DUOX1.
Gene References into Functions
  1. The proliferation and migration of granule cells was delayed after P15 in Duoxa-/- mice. However, these changes disappeared by P25. Although the cerebellar structure of Duoxa-/- mice was not significantly different from that of Wt mice at P25, motor coordination was impaired. It was also found that the amplitude of paired-pulse facilitation at parallel fiber-Purkinje cell synapses decreased in Duoxa-/- mice. PMID: 26914863
  2. DUOXA1 overexpression in muscle stem cells induces apoptosis and inhibits differentiation through DUOX1 and ASK1. PMID: 24410844
  3. DUOXA1 is a novel p53-regulated neurogenic factor involved in p53 dependent neuronal differentiation. PMID: 21362455
  4. Nip1 has an important role in the guidance of neuronal differentiation through ROS generation and modulation of intermediate filaments PMID: 20233719
Subcellular Location
Membrane; Multi-pass membrane protein.
Protein Families
DUOXA family
Database Links
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