Recombinant Mouse Vesicle transport through interaction with t-SNAREs homolog 1A(Vti1a)

Code CSB-CF025942MO
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. O89116
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Species Mus musculus (Mouse)
Sequence MSSDFEGYEQDFAVLTAEITSKIARVPRLPPDEKKQMVANVEKQLEEARELLEQMDLEVREIPPQSRGMYSNRMRSYKQEMGKLETDFKRSRIAYSDEVRNELLGDAGNSSENQRAHLLDNTERLERSSRRLEAGYQIAVETEQIGQEMLENLSHDREKIQRARDRLRDADANLGKSSRILTGMLRRIIQNRILLVILGIIVVIAILTAIAFFVKGH
Source in vitro E.coli expression system
Gene Names Vti1a
Protein Names Recommended name: Vesicle transport through interaction with t-SNAREs homolog 1A Alternative name(s): Vesicle transport v-SNARE protein Vti1-like 2 Vti1-rp2
Expression Region 1-217
Tag Info N-terminal 10xHis-tagged
Protein Description full length protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. Involved in vesicular transport from the late endosomes to the trans-Golgi network. Along with VAMP7, involved in an non-conventional RAB1-dependent traffic route to the cell surface used by KCNIP1 and KCND2. May be concerned with increased secretion of cytokines associated with cellular senescence.
Subcellular Location Golgi apparatus membrane, Single-pass type IV membrane protein
Protein Families VTI1 family
Tissue Specificity Widely expressed.
Database Links

KEGG: mmu:53611

STRING: 10090.ENSMUSP00000093644

UniGene: Mm.258637

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