Recombinant Pig Prostaglandin E2 receptor EP3 subtype (PTGER3)

Code CSB-CF018972PI
MSDS
Size Pls inquire
Source in vitro E.coli expression system
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Product Details

Target Names
PTGER3
Uniprot No.
Alternative Names
PTGER3; Prostaglandin E2 receptor EP3 subtype; PGE receptor EP3 subtype; PGE2 receptor EP3 subtype; Prostanoid EP3 receptor
Species
Sus scrofa (Pig)
Expression Region
1-373
Target Protein Sequence
MWAPERSAEEQGNLTRSLGSSEDCGSVSVVFPMTMLITGFVGNALAMLLVSQSYRRRESK RKKSFLLCIGWLALTDMVGQLLTSPVVIVLYLSHQRWEQLDPSGRLCTFFGLTMTAFGLS SLFIASAMAVERALAIRAPHWYSSHMKTSATRAVLLGVWLAVLAFALLPVLGVGQYTIQW PGTWCFISTRTGGNETSSENNWGNIFFASAFSFLGLSALVVTFACNLATIKALVSRCRAK ATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLIMMLKTIFNQTSVEYCKVYTEKQN ECNFFLIAVRLASLNQILDPWVYLLLRKILLQKFCQAVSQKQREEAATLIFTHLSISRTE PGEARVLFSKSKC
Protein Length
Full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

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Target Background

Function
Receptor for prostaglandin E2 (PGE2). Required for normal development of fever in response to pyrinogens, including IL1B, prostaglandin E2 and bacterial lipopolysaccharide (LPS). Required for normal potentiation of platelet aggregation by prostaglandin E2, and thus plays a role in the regulation of blood coagulation. Required for increased HCO3(-) secretion in the duodenum in response to mucosal acidification, and thereby contributes to the protection of the mucosa against acid-induced ulceration. Not required for normal kidney function, normal urine volume and osmolality.
Gene References into Functions
  1. vasoconstriction is mediated by phosphatidyl-inositol pathway via activation of EP1- and EP3-receptors located on the smooth muscle cells PMID: 15625406
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Families
G-protein coupled receptor 1 family
Database Links
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