Recombinant Rat Embigin(Emb)

Code CSB-CF007631RA
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. O88775
Storage Buffer Tris-based buffer,50% glycerol
Species Rattus norvegicus (Rat)
Sequence DPADSAFTSLPVREEMMAKYANLSLETYNISLTEQTRVSEQNITLERPSHLELECTFTATEDVMSMNVTWKKDDALLETTDGFNTTKMGDTLYSQYRFTVFNSKQMGKYSCFLGEELRGTFNIRVPKVHGKNKPLITYVGDSTVLKCECQNCLPLNWTWYMSNGTAQVPIDVHVNDKFDINGSYANETKLKVKHLLEEDGGSYWCRAAFPLGESEEHIKLVVLSFMVPLKPFLAIIAEVILLVAIILLCEVYTQKKKNDPDDGKEFEQIEQLKSDDSNGIENNVPRYRKTDSGDQ
Source in vitro E.coli expression system
Gene Names Emb
Protein Names Recommended name: Embigin
Expression Region 34-328
Tag Info N-terminal 10xHis-tagged
Protein Description Full Length of Mature Protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Plays a role in the outgrowth of motoneurons and in the formation of neuromuscular junctions. Following muscle denervation, promotes nerve terminal sprouting and the formation of additional acetylcholine receptor clusters at synaptic sites without affecting terminal Schwann cell number or morphology. Delays the retraction of terminal sprouts following re-innervation of denervated endplates (By similarity). Plays a role in targeting the monocarboxylate transporters SLC16A1 and SLC16A7 to the cell membrane.
Subcellular Location Cell membrane, Single-pass type I membrane protein, Cell junction, synapse
Tissue Specificity Detected in prostate, mammary gland and erythrocytes (at protein level). Detected in testis, brain, prostate, heart, kidney, liver, mammary gland and lung.
Database Links

KEGG: rno:114511

STRING: 10116.ENSRNOP00000015306

UniGene: Rn.16221

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