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Recombinant Meyerozyma guilliermondii Ubiquitin-like modifier-activating enzyme ATG7 (ATG7), partial

Recombinant Meyerozyma guilliermondii Ubiquitin-like modifier-activating enzyme ATG7 (ATG7), partial

Code	002294MTM
Size	20μg/100μg/1mg
Price	Request a Quote or Start an on-line Chat
Trial Size	24T ELISA Kit Trial Size (Only USD$150/ kit) * The sample kit cost can be deducted from your subsequent orders of 96T full size kits of the same analyte at 1/5 per kit, until depleted in 6 months. Apply now

Product Details
Customer Reviews and Q&A
Target Background

Product Details

Alternative Names

ATG7; PGUG_04077Ubiquitin-like modifier-activating enzyme ATG7; ATG12-activating enzyme E1 ATG7; Autophagy-related protein 7

Uniprot No.

A5DLC6

Species

Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii)

Assay Principle

N-terminal His-tagged/Tag-Free

Measurement

Partial

Troubleshooting
and FAQs

ELISA kit FAQs

Storage

Store at 2-8°C. Please refer to protocol.

Customer Reviews and Q&A

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Target Background

Function
(From Uniprot)

E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Plays a role in the regulation of filamentous growth and chronological longevity.

Subcellular Location

Cytoplasm. Preautophagosomal structure.

Protein Families

ATG7 family

Database Links

KEGG: pgu:PGUG_04077

STRING: 4929.A5DLC6

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The Overview of Autophagy Crosstalk Between Autophagy and Apoptosis CUSABIO's Five Expression Systems General Information of Different Tags How to express a protein with bioactivity? How to choose a suitable expression vector? Applications of recombinant proteins Production of Recombinant Protein

Related pathways

Autophagy

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