RRP1 Antibody

Code CSB-PA020526GA01HU
Size 100μl
Price Request a Quote or Start an on-line Chat
Trial Size 24T ELISA Kit Trial Size (Only USD$150/ kit)
* The sample kit cost can be deducted from your subsequent orders of 96T full size kits of the same analyte at 1/5 per kit, until depleted in 6 months. Apply now

Product Details

Alternative Names
D21S2056E antibody; NNP 1 antibody; NNP-1 antibody; NNP1 antibody; Nnp1 homolog nucleolar protein antibody; NOP52 antibody; Novel nuclear protein 1 antibody; Nucleolar protein Nop52 antibody; Nucleolar protein, 52-KD antibody; Protein NNP 1 antibody; Protein NNP1 antibody; Ribosomal RNA processing 1 antibody; Ribosomal RNA processing 1 homolog antibody; Ribosomal RNA processing 1 homolog (S. cerevisiae) antibody; Ribosomal RNA processing protein 1 homolog A antibody; Ribosomal RNA processing protein 1, S. cerevisiae, homolog of antibody; rrp1 antibody; RRP1 like protein antibody; RRP1-like protein antibody; RRP1_HUMAN antibody; RRP1A antibody
Abbreviation
RRP1
Uniprot No.
Species
Homo sapiens (Human)
Troubleshooting
and FAQs
Storage
Store at 2-8°C. Please refer to protocol.

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Target Background

Function
(From Uniprot)
Plays a critical role in the generation of 28S rRNA.
Gene References into Functions
  1. The data suggest that RRP1 is involved not only in competitive binding with fibrillarin to C1QBP on 90S but also in site 2 cleavage in ITS1 of pre-rRNAs at early stages of human ribosome biogenesis. PMID: 25969445
  2. p32 is a new rRNA maturation factor involved in the remodeling from pre-90S particles to pre-40S and pre-60S particles that requires the exchange of FBL for Nop52. PMID: 21536856
  3. NNP-1 expression in neuroblastoma PMID: 12209604
Subcellular Location
Nucleus, nucleolus.
Protein Families
RRP1 family
Tissue Specificity
Ubiquitously expressed in fetal and adult tissues.
Database Links

HGNC: 18785

OMIM: 610653

KEGG: hsa:8568

STRING: 9606.ENSP00000417464

UniGene: Hs.110757

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