Study identifies Amot's role in regulating a key signaling pathway
Study identifies Amot's role in regulating a key signaling pathwayMulti-cellular organisms consist of more than one cell. All species of animals are multi-cellular. But how do cells in animals know when and where to grow and divide? Individual cells communicate with each other and t...
Detailed information

BDNF mutation may contribute to cognitive decline
BDNF mutation may contribute to cognitive declineA team of researchers from the University of Wisconsin School of Medicine and Public Health and the University of California has found that individuals at risk of developing Alzheimer's disease who carry a specific gene ...
Detailed information

Tofacitinib might be used in the treatment of ulcerative colitis
Tofacitinib might be used in the treatment of ulcerative colitisUlcerative colitis (UC), a common form of inflammatory bowel disease, primarily affects the colon. The Crohn's and Colitis Foundation says that approximately 700,000 people in the United States have UC. The disease is ch...
Detailed information

Why virus infection increases the risk of asthma attacks?
Why virus infection increases the risk of asthma attacks?Asthma is one of the most common inflammatory diseases of the airways and its incidence is increasing throughout the world. It is estimated that 10% of adults in developed countries have asthma, and the morbility of asth...
Detailed information

Blocking m2R receptors may be a way to treat Spinal Muscular Atrophy
Blocking m2R receptors may be a way to treat Spinal Muscular AtrophyA recent study appearing in eLife shows that the m2R receptors could be a therapeutic target for Spinal Muscular Atrophy (SMA), a genetic disease that attacks motor neurons in the spinal cord. SMA occurs in 1 in 10,00...
Detailed information

Study links high Bcl-3 levels to inflammatory bowel disease
Study links high Bcl-3 levels to inflammatory bowel diseaseIncreased expression of the protein Bcl-3 may result in inflammatory bowel disease (IBD), according to a study published in Nature Communications. This work is conducted by researchers from the University of Mainz, Unive...
Detailed information

Combination treatment prolongs survival in mice with human ovarian cancer tumors
Combination treatment prolongs survival in mice with human ovarian cancer tumorsHigh-grade serous carcinoma (HGSC) is the most malignant form of ovarian cancer, accounting for 70% cases. Most patients with this form of ovarian cancer have a therapeutic response to platinum drugs, which are now a mai...
Detailed information

Special bacterial interaction could be utilized to treat cystic fibrosis
Special bacterial interaction could be utilized to treat cystic fibrosisPublished 27 April 2017 in PLoS Pathogens, a research has demonstrated the interactions between different types of bacteria that infect the lungs in cystic fibrosis (CF), an inherited disease that affects mostly the lung...
Detailed information

New insight into brain inflammation in neurological diseases
New insight into brain inflammation in neurological diseasesInflammation in the brain is found in a range of neurological diseases, such as Alzheimer's disease, Parkinson's disease, Amyotrophic lateral sclerosis, multiple sclerosis, and stroke. But the cause of the inflammation a...
Detailed information

IFN-γ produced by T cells induces regression of tumor blood vessels
IFN-γ produced by T cells induces regression of tumor blood vesselsImmunotherapy, or called biological therapy, is a type of treatment that utilizes the body's own immune system to fight cancer. Compared with chemotherapy drugs, immunotherapy regiments generally have fewer short-term si...
Detailed information

p53 affects the extent of liver damage and tissue repair after acetaminophen overdose
p53 affects the extent of liver damage and tissue repair after acetaminophen overdoseResearchers at the University of Kansas Medical Center have demonstrated that the p53 protein impacts the progression of liver damage as well as tissue repair after an acetaminophen (APAP) overdose. APAP is a pain med...
Detailed information

Low NPTX2 is associated with memory loss in AD
Low NPTX2 is associated with memory loss in ADA collaborative team led by Paul Worley at Johns Hopkins University School of Medicine has demonstrated that low levels of the protein NPTX2 in the brain are associated with cognitive decline in individuals with Alzheime...
Detailed information

Research sheds light on mechanism of intellectual disability
Research sheds light on mechanism of intellectual disabilityResearchers from the US and Canada have found that a specific protein plays a role in maintaining the balance of neuron communication, a finding that may lead to new therapies for neurodevelopmental diseases such as inte...
Detailed information

Foxo3 appears to protect outer hair cells from noise damage
Foxo3 appears to protect outer hair cells from noise damageA team of researchers from the University of Rochester School of Medicine and Dentistry, the University College London, and Ortho Clinical Diagnostics has demonstrated that a protein associated with human longevity helps...
Detailed information

Chemicals in pepper and cannabis reduce gut inflammation
Chemicals in pepper and cannabis reduce gut inflammationResearchers have found that chemicals in pepper and cannabis can calm the gut immune system, a discovery that may offer new leads for finding drugs for diabetes and colitis. The study, published in the Proceedings of the...
Detailed information

Enzyme AMCase protects the body against chitin
Enzyme AMCase protects the body against chitinA study from the University of California has demonstrated that an enzyme secreted by lung epithelial cells protects us from chitin, a compound found in many places throughout the world. Chitin is a nitrogen-containin...
Detailed information

KCNQ1 is associated with good survival in colorectal cancer
KCNQ1 is associated with good survival in colorectal cancerColorectal cancer, or called colon cancer for short, is a type of cancer that occurs in the colon or rectum. Colorectal cancer is the third most frequent malignancy worldwide. It is responsible for approximately 774,000 ...
Detailed information

Malaria protein is a useful tool in the fight against drug-resistant bladder cancer
Malaria protein is a useful tool in the fight against drug-resistant bladder cancerA protein found in the malaria parasite shows a significant therapeutic effect on bladder cancer, according to a study published in European Urology. The study is conducted by an international team consisting of research...
Detailed information

Potent dual inhibitors of TNF and RANKL identified
Potent dual inhibitors of TNF and RANKL identifiedUsing a computer-based drug screening platform, researchers have identified two compounds capable of blocking proteins involved in chronic inflammatory diseases. The study is published 20 April 2017 in PLoS Computational...
Detailed information

A frog protein protects mice against flu infection
A frog protein protects mice against flu infectionEmory University researchers have found that a frog slime protein can kill flu virus. The study, published in Immunity, demonstrates that a peptide from the skin of the South Indian frog, named "urumin", is virucidal for...
Detailed information

A protein in umbilical cord blood appears to improve mental ability
A protein in umbilical cord blood appears to improve mental abilityA protein found in human umbilical cord blood can make old mice smarter, a finding that may lead to new therapies for aging-related declines in mental ability, according to a study published in the scientific journal Nat...
Detailed information

Study provides new clues to IBD therapy
Study provides new clues to IBD therapyA recent study published 22 March 2017 in the journal Mucosal Immunity has revealed that a specific cytokine controls whether immune cells promote or inhibit inflammatory bowel disease (IBD). The study is led by Tim Denn...
Detailed information

Novel LOX inhibitor shows promise in treating cancer
Novel LOX inhibitor shows promise in treating cancerResearchers from the University of Manchester and The Institute of Cancer Research have identified a new pathway involved in the progression of breast cancer, and they have also designed a compound that inhibits this pat...
Detailed information

Scientists find a way to treat motor neuron diseases
Scientists find a way to treat motor neuron diseasesResearchers from the Harvard University and Columbia University have shown that two different neurodegenerative diseases, spinal muscular atrophy (SMA) and amyotrophic lateral sclerosis (ALS), may be treated with a commo...
Detailed information

Approach to removing pathogenic antibodies in anti-MAG neuropathy
Approach to removing pathogenic antibodies in anti-MAG neuropathyAccording to a study published in the Proceeding of the National Academy of Science, synthetic carbohydrates may be used to treat anti-MAG neuropathy, an autoimmune disease of the peripheral nervous system. Anti-MAG n...
Detailed information

Measuring TSPYL5 levels may help treat prostate cancer
Measuring TSPYL5 levels may help treat prostate cancer Prostate cancer is the most frequently diagnosed malignancy in adult men in developed countries. For example, in the US, one out of five men will be diagnosed with prostate cancer. Even though mortality has fallen signif...
Detailed information

Combining an experimental vaccine with an existing drug increases survival of patients with glioblastoma
Combining an experimental vaccine with an existing drug increases survival of patients with glioblastomaGlioblastoma is the most common malignant brain tumor in adults. The disease is almost uniformly fatal, and the median survival is less than 15 months. Despite great breakthroughs in basic cancer research, the therapies ...
Detailed information

Excessive Id1 protein may increase the risk of obesity
Excessive Id1 protein may increase the risk of obesityThe protein inhibitor of differentiation 1 (Id1) is a member of the basic HLH family of transcription factors. This protein is known to promote proliferation and inhibit differentiation. Upregulation of Id1 expression ha...
Detailed information

Inhibition of ataxin-2 prolongs survival of mice with ALS
Inhibition of ataxin-2 prolongs survival of mice with ALSAccording to a study published online 12 April 2017 in the journal Nature, reduction of a certain protein prolongs survival time of mice with Amyotrophic lateral sclerosis (ALS). The study, carried out by scientists f...
Detailed information

Cell replacement therapy treats Parkinson's disease in mice
Cell replacement therapy treats Parkinson's disease in miceAn international research team has found a treatment approach for Parkinson's disease, a progressive neurodegenerative disease characterized by the loss of dopamine-producing neurons in the brain. The study, described...
Detailed information

Gene that increases chemotherapy effectiveness identified
Gene that increases chemotherapy effectiveness identifiedA gene called PID1 may increase the therapeutic effect of chemotherapy drugs on brain tumors, according to a study published online 11 April 2017 in the journal Scientific Reports. There are several treatment options ...
Detailed information

PLK4 inhibition could be a way to treat rhabdoid tumors
PLK4 inhibition could be a way to treat rhabdoid tumorsA team of researchers from Ann and Robert H. Lurie Children's Hospital of Chicago, Stanley Manne Children's Research Institute, Northwestern University, Thermo Fisher Scientific, and Juntendo University has identified a ...
Detailed information

Research opens a new avenue for treatment of leukemia
Research opens a new avenue for treatment of leukemiaIn a paper in the journal Nature Immunology, researchers describe how a protein, called STAT5, can drive the development of leukemia, a cancer of the blood cells that usually starts in the bone marrow. The study, carr...
Detailed information

New method shows promise against HIV
New method shows promise against HIVResearchers in the US and China have developed a method that renders cells resistant to virus infection, according to a study published in the Proceedings of the National Academy of Sciences. The study, carried out by...
Detailed information

Scientists reveal the role of the c-Fos protein in hepatocellular carcinoma
Scientists reveal the role of the c-Fos protein in hepatocellular carcinomaDescribed in the Journal of Experimental Medicine, a recent study demonstrates that a protein called c-Fos is necessary for the development of hepatocellular carcinoma (HCC), the dominant form of primary liver cancer. ...
Detailed information

BATF2 protein prevents tissue damage during parasitic infection
BATF2 protein prevents tissue damage during parasitic infectionChagas disease, which is caused by the protozoan Trypanosoma cruzi, is considered a neglected parasitic infection. The disease is mainly found in South America, and that's why it is also called American trypanosomiasis. ...
Detailed information

Study details how a protein enhances vaccine effectiveness
Study details how a protein enhances vaccine effectiveness In a paper published in Scientific Reports, investigators report a protein that has the ability to enhance the effectiveness of vaccines. The study, carried out by investigators from the Boston University School of Medic...
Detailed information

TNF influences blood pressure, study finds
TNF influences blood pressure, study findsA paper appearing in Nature Communications reports a new role of the cytokine tumor necrosis factor, abbreviated TNF. The study, carried out by a collaborative team headed by Steffen-Sebastian Bolz from the University of...
Detailed information

Study links a gene variant to sleep disorder
Study links a gene variant to sleep disorderResearchers from The Rockefeller University, Weill Cornell Medical College, and Bilkent University have identified a gene variant associated with delayed sleep phase disorder (DSPD), a common sleep disorder where a perso...
Detailed information

hERG1 protein seems to be associated with cancer metastasis
hERG1 protein seems to be associated with cancer metastasisInvestigators from the University of Milano-Bicocca, University of Firenze, Leiden University, University of Torino, and several other institutions have identified a protein associated with cancer metastasis. The protein...
Detailed information

Compounds in fruit have anti-TB properties
Compounds in fruit have anti-TB propertiesAccording to a study published in the European Journal of Medicinal Chemistry, amphiphilic xanthones found in mangosteens (a kind of fruit) may have therapeutic effects on the common infectious disease tuberculosis (TB),...
Detailed information

Researchers pinpoint a potential therapeutic target for acral lentiginous melanoma
Researchers pinpoint a potential therapeutic target for acral lentiginous melanomaPublished in the journal Genome Research, a study reveals a genetic link to acral lentiginous melanoma (ALM), a rare but aggressive form of melanoma. ALM arises on the palms and soles, beneath the nails, or in the ora...
Detailed information

New biomarker of and therapeutic target for inflammatory bowel disease
New biomarker of and therapeutic target for inflammatory bowel diseaseInflammatory bowel diseases (IBD) is a group of disorders in which the intestines become inflamed. This inflammation can lead to symptoms such as abdominal pain, diarrhea, bleeding from the rectum, loss of appetite, weig...
Detailed information

Plasmapheresis may help treat antibiotic resistant infections
Plasmapheresis may help treat antibiotic resistant infectionsIn a paper in the American Journal of Respiratory and Critical Care Medicine, a team led by researchers at the University of Birmingham describes an approach to fight against antibiotic resistant bacteria. Pseudomonas...
Detailed information

Discovery of new gene mutations may improve treatment of a rare cancer
Discovery of new gene mutations may improve treatment of a rare cancerA study, led by the National Institutes of Health (NIH) researchers and published online in the journal Blood Advances, has identified new genes associated with a rare but potentially fatal disease, Erdheim-Chester disea...
Detailed information

Inclisiran helps control the levels of
Inclisiran helps control the levels of A phase 2 clinical trial has shown that a single dose of inclisiran, a new drug designed to target PCSK9 messenger RNA, lowers PCSK9 and low-density lipoprotein (LDL) cholesterol levels in patients at high risk for cardi...
Detailed information

Mayo researchers identify a marker for amyotrophic lateral sclerosis
Mayo researchers identify a marker for amyotrophic lateral sclerosisDescribed in the latest version of Science Translational Medicine, a study led by Mayo Clinic researchers has shown that a protein called polyGP might be a useful pharmacodynamic marker for a specific form of amyotrophic...
Detailed information

PRMT1: a potential target for pancreatic cancer
PRMT1: a potential target for pancreatic cancerResearchers at the University of Texas M. D. Anderson Cancer Center have demonstrated that the protein arginine methyltransferase 1 (PRMT1) can be targeted to combat the most common malignancy of the pancreas, pancreatic...
Detailed information

Structure of a protein that triggers cystic fibrosis solved by researchers
Structure of a protein that triggers cystic fibrosis solved by researchersA team consisting of researchers from The Rockefeller University in the USA and Semmelweis University in Hungary now has solved the three-dimensional structure of the cystic fibrosis transmembrane conductance regulator (...
Detailed information

FAK/MYO1E interaction promotes cancer metastasis
FAK/MYO1E interaction promotes cancer metastasisScientists have identified a possible Achilles' heel for cancer. The study, led by scientists from Mayo Clinic, University of Tuebingen, and University of Copenhagen, and published in March 2017 in the Proceedings of the...
Detailed information

Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
Address
7505 Fannin St. Ste 610-312, Houston, TX 77054, USA
Join Us with

Subscribe newsletter

Leave a message

© 2007-2022 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1