ATG9A (Autophagy Related 9A) is a Protein Coding gene. Diseases associated with ATG9A include Age-Related Hearing Loss and Neurodegeneration With Brain Iron Accumulation 5. Among its related pathways are Autophagy - animal and Autophagy Pathway. Gene Ontology (GO) annotations related to this gene include heme-copper terminal oxidase activity. An important paralog of this gene is ATG9B.
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ATG9A Antibodies for Homo sapiens (Human)
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Autophagy-related protein 9A is a protein in humans that is encoded by the ATG9A gene. The ATG9A protein is involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. It plays a key role in the organization of the pre-autophagosomal structure/phagophore assembly site (PAS), the nucleating site for the formation of the sequestering vesicle. ATG9A cycles between a juxta-nuclear trans-Golgi network compartment and late endosomes. Nutrient starvation induces accumulation on autophagosomes. Starvation-dependent trafficking requires ULK1, ATG13, and SUPT20H.