Atg4b

The following Atg4b reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

Atg4b Antibodies

Atg4b Antibodies for Homo sapiens (Human)

Atg4b Antibodies for Arabidopsis thaliana (Mouse-ear cress)

Atg4b Antibodies for Oryza sativa subsp. indica (Rice)

Atg4b Antibodies for Oryza sativa subsp. japonica (Rice)

Atg4b Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)

Atg4b Proteins

Atg4b Proteins for Oryza sativa subsp. indica (Rice)

Atg4b Proteins for Xenopus laevis (African clawed frog)

Atg4b Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

Atg4b Proteins for Bos taurus (Bovine)

Atg4b Proteins for Gallus gallus (Chicken)

Atg4b Proteins for Oryza sativa subsp. japonica (Rice)

Atg4b Proteins for Mus musculus (Mouse)

Atg4b Proteins for Arabidopsis thaliana (Mouse-ear cress)

Atg4b Background

Cysteine protease ATG4B is a protein in humans that is encoded by the ATG4B gene. Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2, and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. It has also an activity of the delipidating enzyme for the PE-conjugated forms.

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