BECN1 Antibodies

BECN1 (Beclin 1) is a Protein Coding gene. Diseases associated with BECN1 include Sphingolipidosis and Cervix Carcinoma. Among its related pathways are Metabolism of proteins and Autophagy - animal. Gene Ontology (GO) annotations related to this gene include sequence-specific DNA binding and phosphatidylinositol 3-kinase binding. An important paralog of this gene is BECN2.

CUSABIO produces high-quality anti-BECN1 antibodies (includes polyclonal antibodies, monoclonal antibodies, recombinant antibodies) in house with strict quality control. And they can help you discover more in your research.
These BECN1 antibodies are validated in multiple tissues with various applications and covering a broad range of life science research and drug development. They are featured with high specificity, multiple epitopes recognition, and wide species reactivity. Moreover, CUSABIO provides various options on sizes, excellent technical support and BECN1 antibodies custom service.

BECN1 Antibodies Catalog

BECN1 Antibodies for Homo sapiens (Human)

BECN1 Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)

BECN1 Antibodies for Mus musculus (Mouse)

BECN1 Background

Beclin-1 is a protein in humans that is encoded by the BECN1 gene. The BECN1 protein is a mammalian ortholog of the yeast autophagy-related gene 6 (Atg6) and BEC-1 in the C. elegans nematode. This protein interacts with either BCL-2 or PI3k class III, playing a critical role in the regulation of both autophagy and cell death. BECN1 also plays a central role in autophagy. In addition to its role in autophagy, BECN1 is an important player in tumorigenesis, and neurodegeneration, being implicated in the autophagic programmed cell death. Ovarian cancer with upregulated autophagy has a less aggressive behavior and is more responsive to chemotherapy. Schizophrenia is associated with low levels of BECN1 in the hippocampus of the affected which causes diminished autophagy which in turn results in increased neuronal cell death.

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