BRAF Antibodies

BRAF is a member of the RAF family of serine/threonine protein kinases. As a part of the RAS/RAF/MEK/ERK pathway, BRAF transduces signals from RAS to ERK, eventually triggering many biological activities such as cell differentiation, proliferation, and apoptosis. BRAF is also considered as an oncogene whose mutations cause the aberrant activation of BRAF kinase, leading to sustained activation of the MAPK signaling pathway contributing to the growth and proliferation of carcinomatous cells. Therefore, numerous cancers are correlated with BRAF mutations. Anti-BRAF antibodies can detect the endogenous levels of BRAF protein and be used in the studies on cancer.

CUSABIO provides 22 anti-BRAF antibodies, including 21 polyclonal antibodies and 1 recombinant antibody. They are quality tested in ELISA, WB, IHC, and IF applications and show reactivity with Human, Mouse, and Rat species. Like all polyclonal antibodies, the polyclonal BRAF antibodies are more sensitive to BRAF protein. The 8 phosphorylated BRAF antibodies also have the ability to detect the phosphorylation of a BRAF protein. And the recombinant BRAF antibody has high specificity and low cross-reactivity with the BRAF homologs. Some BRAF antibodies are conjugated with HRP, FITC, Biotin labeling molecules, which are helpful in the downstream analysis.

In order to meet the various experimental needs of customers as much as possible, we also provide customized services.

BRAF Antibodies Catalog

BRAF Antibodies for Homo sapiens (Human)

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