CAMKK2 Proteins

CAMKK2 (Calcium/Calmodulin Dependent Protein Kinase Kinase 2) is a Protein Coding gene. Diseases associated with CAMKK2 include Parkinson Disease, Late-Onset. Among its related pathways are Oxytocin signaling pathway and Autophagy - animal. Gene Ontology (GO) annotations related to this gene include calcium ion binding and protein kinase activity. An important paralog of this gene is CAMKK1.

The following recombinant CAMKK2 proteins are manufactured in house under a complete QC system by CUSABIO. They are expressed by Yeast, E.coli, Baculovirus, Mammalian cell, In Vivo Biotinylation in E.coli. Highlights of these recombinant CAMKK2 proteins as follow:
High purity, Low endotoxin, Multiple Tags, Animal-free, Wide applications (Cell assay, Protein-protein interaction, Drug-related studies, Enzymatic activity in vitro, Protein structure analysis, etc.)
In addition, various options on sizes, excellent technical support, and recombinant CAMKK2 proteins custom service will be also offered.

CAMKK2 Proteins Catalog

CAMKK2 Proteins for Rattus norvegicus (Rat)

CAMKK2 Proteins for Mus musculus (Mouse)

CAMKK2 Proteins for Homo sapiens (Human)

CAMKK2 Background

Calcium/calmodulin-dependent protein kinase kinase 2 is a protein in humans that is encoded by the CAMKK2 gene. The CAMKK2 is a calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in many cellular processes. CAMKK2 isoform 1, isoform 2, and isoform 3 can phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. Efficiently phosphorylates 5'-AMP-activated protein kinase (AMPK) trimer, including that consisting of PRKAA1, PRKAB1, and PRKAG1. This phosphorylation is stimulated in response to Ca(2+) signals (By similarity). It seems to be involved in hippocampal activation of CREB1 (By similarity).


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