CD14 Proteins

CD14 is a glycoprotein expressed on the cell surface in a glycosylphosphatidylinosotol (GP1)-anchored manner. It also exists as a soluble form present in the circulation and other body fluids. CD14 facilitates TLR4 activation by PAPMs (pathogen-associated molecular patterns) such as lipopolysaccharide endotoxins (LPS) of Gram-negative bacteria. LPS activation of TLR4 ultimately leads to the occurrence of a series of cascades, including tyrosine phosphorylation, NF kappa B translocation, cytokine release, and oxygen free radical production.

CUSABIO provides 25 recombinant CD14 proteins covering multiple species. Among these proteins, there are 5 Human-origin CD14 proteins, 5 Rabbit-origin CD14 proteins, 5 Mouse-origin CD14 proteins, 5 Rat-origin CD14 proteins, and 5 Bovine-origin CD14 proteins. The purity of some CD14 proteins is greater than 90%, while overall purity is over 85%. They are all expressed in five expression systems, including Yeast, E.coli, Baculovirus, Mammalian cell, In Vivo Biotinylation in E.coli. And their expression regions include Human CD14 protein (20-367aa and 20-345aa), Rabbit/Rat CD14 protein(18-342aa), Mouse CD14 protein (16-336aa), and Bovine CD14 protein (21-373aa). Several human CD14 proteins can find use in the studies of immunology. Some proteins carry different tags on the N- or C-terminus, such as N-terminal GST-tag and N-terminal 6xHis-tag. CD14 proteins that do not have tags or carry custom tags are also available.

All our products are guaranteed in high quality, you can rest assured to buy. In addition, various options on sizes, excellent technical support, and recombinant CD14 proteins custom service will be also offered.

CD14 Proteins Catalog

CD14 Proteins for Mus musculus (Mouse)

CD14 Proteins for Homo sapiens (Human)

CD14 Proteins for Oryctolagus cuniculus (Rabbit)

CD14 Proteins for Rattus norvegicus (Rat)

CD14 Proteins for Bos taurus (Bovine)

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