Calcium/calmodulin-dependent protein kinase type II subunit beta is a protein in humans that is encoded by CAMK2B gene. Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in dendritic spine and synapse formation, neuronal plasticity and regulation of sarcoplasmic reticulum Ca(2+) transport in skeletal muscle. In neurons, plays an essential structural role in the reorganization of the actin cytoskeleton during plasticity by binding and bundling actin filaments in a kinase-independent manner. This structural function is required for correct targeting of CaMK2A, which acts downstream of NMDAR to promote dendritic spine and synapse formation and maintain synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning. In developing hippocampal neurons, promotes arborization of the dendritic tree and in mature neurons, promotes dendritic remodeling.
The following Camk2b reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
Camk2b Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA004466GA01HU | CAMK2B Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA283993 | Phospho-CAMK2B/CAMK2G/CAMK2D (Thr287) Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA362118 | CAMK2B Antibody |
Human,Mouse,Rat | ELISA,IHC |
CSB-PA061493 | CAMK2B Antibody |
Human,Mouse,Rat | ELISA,IHC |
CSB-PA618786ESR2HU | CAMK2B Antibody |
Human | ELISA, IHC |
Camk2b Antibodies for Mus musculus (Mouse)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA004466XA01MO | Camk2b Antibody |
Mus musculus (Mouse) | ELISA, WB (ensure identification of antigen) |
Camk2b Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP004466MO CSB-EP004466MO CSB-BP004466MO CSB-MP004466MO CSB-EP004466MO-B |
Recombinant Mouse Calcium/calmodulin-dependent protein kinase type II subunit beta (Camk2b) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Camk2b Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP004466RA CSB-EP004466RA CSB-BP004466RA CSB-MP004466RA CSB-EP004466RA-B |
Recombinant Rat Calcium/calmodulin-dependent protein kinase type II subunit beta (Camk2b) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Camk2b Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP618786HU CSB-EP618786HU CSB-BP618786HU CSB-MP618786HU CSB-EP618786HU-B |
Recombinant Human Calcium/calmodulin-dependent protein kinase type II subunit beta (CAMK2B) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Camk2b Proteins for Bos taurus (Bovine)
Code | Product Name | Source |
---|---|---|
CSB-YP662131BO CSB-EP662131BO CSB-BP662131BO CSB-MP662131BO CSB-EP662131BO-B |
Recombinant Bovine Calcium/calmodulin-dependent protein kinase type II subunit beta (CAMK2B), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |